Appointments
 
Assistant Professor of Cell and Developmental Biology

 
Weill Cornell \r\nPhysician
   

Nibu, Yutaka
 (212) 746-6184  (212) 746-8175

1. Nibu, Y., Takahashi, S., Tanimoto, K., Murakami, K., and Fukamizu, A. Identification of cell type-dependent enhancer core element located in the 3'-downstream region of the human angiotensinogen gene. J. Biol. Chem. 269, 28598-28605 (1994).

2. Nibu, Y., Tanimoto, K., Takahashi, S., Ono, H., Murakami, K., and Fukamizu, A. A cell type-dependent enhancer core element is located in exon 5 of the human angiotensinogen gene. Biochem. Biophys. Res. Commun. 205, 1102-1108 (1994).

3. Nibu, Y., Satoh, T,. Nishi, Y., Takeuchi, T,. Murata, K., and Kusakabe, I. Purification and characterization of extracellular alginate lyase from Enterobacter cloacae M-1. Biosci. Biotech. Biochem. 59, 632-637 (1995).

4. Kobayashi, S., Ohnishi, J., Nibu, Y., Nishimatsu, S., Umemura, S., Ishii, M., Murakami, K., and Miyazaki, H. Cloning of the rat angiotensin II type 2 receptor gene and identification of its functional promoter region. Biochim. Biophys. Acta 1262, 155-158 (1995).

5. Yanai, K., Nibu, Y., Murakami, K., and Fukamizu, A. A cis-acting DNA element located between TATA box and transcription initiation site is critical in response to regulatory sequences in human angiotensinogen gene. J. Biol. Chem. 271, 15981-15986 (1996).

6. Tanimoto, K., Yoshida, E., Mita, S., Nibu, Y., Murakami, K., and Fukamizu, A. Human Activin beta A gene. Identification of novel 5' exon, functional promoter, and enhancers. J. Biol. Chem. 271, 32760-32769 (1996).

7. Takeuchi, T., Nibu, Y., Murata, K., and Kusakabe, I. Purification and characterization of endo poly (alphaL-guluronate) lyase in the enzyme system from Flavobacterium multivolum. Food Sci. Technol. Int. 3, 22-26 (1997).

8. Takeuchi, T., Nibu, Y., Murata, K., Yoshida, S., and Kusakabe, I. Characterization of a novel alginate lyase from Flavobacterium multivolum K-11. Food Sci. Technol. Int. 3, 288-392 (1997).

9. Nibu, Y., Zhang, H., and Levine, M. Interaction of short-range repressors with Drosophila CtBP in the embryo. Science 280, 101-104 (1998).

10. Nibu, Y., Zhang, H., Bajor, E., Barolo, S., Small, S., and Levine, M. dCtBP mediates transcriptional repression by Knirps, Kr?ppel and Snail in the Drosophila embryo. EMBO J. 17, 7009-7020 (1998).

11. Yanai, K., Hirota, K., Taniguchi-Yanai, K., Shigematsu, Y., Shimamoto, Y., Saito, T., Chowdhury, S., Takiguchi, M., Arakawa, M., Nibu, Y., Sugiyama, F., Yagami, K., and Fukamizu, A. Regulated expression of human angiotensinogen gene by hepatocyte nuclear factor 4 and chicken ovalbumin upstream promoter-transcription factor. J. Biol. Chem. 274, 34605-34612 (1999).

12. Mannervik M, Nibu Y, Zhang H, and Levine M. Transcriptional coregulators in development. Science. 284, 606-609 (1999).

13. Nibu, Y., Zhang, H., and Levine, M. Local action of long-range repressors in the Drosophila embryo. EMBO J. 20, 2246-2253 (2001).

14. Nibu, Y. and Levine, M. CtBP-dependent activities of the short-range Giant repressor in the Drosophila embryo. Proc. Natl. Acad. Sci. USA 98, 6204-6208 (2001).

15. Berman, BP., Nibu, Y., Pfeiffer, BD., Tomancak, P., Celniker, SE., Levine, M., Rubin, GM., and Eisen, MB. Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome. Proc. Natl. Acad. Sci. USA 99, 757-762 (2002).

16. Nibu, Y., Senger, K., and Levine, M. CtBP-independent repression in the Drosophila embryo. Mol. Cell. Biol. 23, 3990-3999 (2003).

17. Date, S., Nibu, Y., Yanai, K., Hirata, J., Yagami, K., and Fukamizu, A. Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogengene. Int. J. Mol. Med. 13, 637-642 (2004).

18. Perrone, L., Aihara, H., and Nibu, Y. Transcriptional repressors and repression mechanisms. In: Gene Expression and Regulation (ed. J. Ma), a Current Scientific Frontiers Book, Higher Education Press (Beijing), in press

19. Aihara, H., Perrone, L., and Nibu, Y. Transcriptional repression by the CtBP corepressor in Drosophila. In: CtBP Family Proteins (ed. D. Chinnadurai), Landes Bioscience (Georgetown, TX), in Press.
   
   
 
 
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