Biography
This researcher is engaged in basic science research and teaching specifically relating to the role of synaptic plasticity in psychiatric disorders and addictive diseases as well as in the development and maintenance of hypertension. This research principally uses electron microscopic immunolabeling and spatial-temporal gene deletion study glutamate NMDA receptor-dependent plasticity in brain regions that are most implicated in these abnormalities. The glutamatergic systems are being investigated with respect to their interactive sites with endocannabinoids and other retrograde signaling molecules as well as classic neurotransmitters such as dopamine and acetylchoine. The information obtained from these studies will expand upon existing knowledge of normal function and the malfunctions induced by opiates and other addictive drugs and/or stress.
