Selected recent publications:
Finnemann, S. C. Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors. EMBO J. 16:4143-4154 (2003).
Chowers, I., Y. H. Kim, R. H. Farkas, T. L. Gunatilaka, A. S. Hackam, P. A. Campochiaro, S. C. Finnemann & D. J. Zack. Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake. Invest. Ophthalmol. Vis. Sci. 45: 2098-2106 (2004).
Nandrot, E. F., Y. H. Kim, S. E. Brodie, X. Huang, D. Sheppard & S. C. Finnemann. Loss of synchronized RPE phagocytosis and age-related blindness in mice lacking avb5 integrin. J. Exp. Med. 200:1539-1545 (2004) (cover image).
Nandrot EF, Anand M, Sircar M, and Finnemann SC. Novel function for avb5 integrin in retinal adhesion and its diurnal peak. Am. J. Phys. Cell Phys. 290: C1256 ?C1262 (2006)
Sun M, Finnemann SC, Febbraio M, Shan L, Annangudi SP, Podrez EA, Hoppe G, Darrow R, Organisciak DT, Salomon RG, Silverstein RL, and Hazen SL. Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: A potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions. J. Biol. Chem. 281:4222-4230 (2006).
Lakkaraju, A, SC Finnemann & E Rodriguez-Boulan. The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells. Proc. Natl. Acad. Sci. USA. 104(26):11026-11031 (2007).
Nandrot, EF, M Anand, D Almeida, K Atabai, D Sheppard & SC Finnemann. Essential role for MFG-E8 as ligand for avb5 integrin in diurnal retinal phagocytosis. Proc. Natl. Acad. Sci. USA. 104(29):12005-12010 (2007).
Chang, Y, & SC Finnemann. Tetraspanin CD81 is required for the avb5 integrin-dependent particle binding step of retinal phagocytosis. In press in: J. Cell Science (2007).

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