Publications
• Xia, J., Peng, Y., Mian, I.S., & Lue, N.F. Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase. Mol. Cell. Biol. 20: 5196-5207, (2000).
• Peng, Y., Mian, I.S., and Lue, N.F. Telomerase processivity as a determinant of telomere length. Molecular Cell 7:1201-1211, (2001).
• Singh, S., Steinberg-Neifach, O., Mian, I.S., and Lue, N.F. Analysis of Candida telomerase: a potential role in telomere end protection. Eukaryotic Cell 1: 967-977, (2002).
• Singh, S., and Lue, N.F. Ever Shorter Telomere 1 (EST1)-dependent reverse transcription by Candida telomerase in vitro: evidence in favor of an activating function. Proc. Natl. Acad. Sci. USA 100: 5718-5723, (2003).
• Bosoy, D., Peng, Y., Mian, I. S., and Lue, N.F. Conserved N-terminal motifs of telomerase reverse transcriptase required for ribonucleoprotein assembly in vivo. J. Biol. Chem. 278: 3882-3890, (2003).
• Lue, N.F., Lin, Y.-C., and Mian, I.S. A conserved telomerase motif in the catalytic domain of telomerase reverse transcriptase is specifically required for repeat addition processivity. Mol. Cell. Biol. 23: 8440-8449, (2003).
• Lue, N.F. Adding to the ends:what makes telomerase processive and how important is it? Bioessay 26: 955-962, (2004).
• Lue, N.F. A physical and functional constituent of telomerase anchor site. J. Biol. Chem., 280: 26586-6591, (2005).
• Lue, N.F., Bosoy, D., Moriarty, T., Autexier, C., Altman, B., and Leng, S. Telomerase can act as a template- and RNA-independent terminal transferase. Proc. Natl. Acad. Sci. USA, 102: 9778-9783, (2005).
• Autexier, C. and Lue, N.F. The structure and function of telomerase reverse transcriptase. Ann. Rev. Biochem., 75: 493-517, (2006).
• Yu, E.Y., Steinberg-Neifach, O., Dandjinou, T.A., Kang, F., Morrison, A., Shen, X., and Lue, N.F. Regulation of telomere structure and function by subunits of the INO80 chromatin remodeling complex. Mol. Cell. Biol., 27: 5639-5649, (2007).
• Hsu, M., Yu, E.Y., Singh, S.M., and Lue, N.F. The mutual dependence of Candida Est1p and Est3p in telomerase assembly and activation. Euk. Cell, 6: 1330-1338 (2007).
• Hsu, M., McEachern, M.J., Dandjinou, T.A., Tzfati, Y., Orr, E., Blackburn, E.H., and Lue, N.F. The Candida albicans telomerase core components protect telomeres from aberrant degradation. Proc. Natl. Acad. Sci. USA, 104: 11682-11687 (2007).
• Lue, N., and Li, Z. Modeling and structure function analysis of the putative anchor site of yeast telomerase. Nucl. Acids Res., 35: 5213-5222 (2007).
• Yu, E., Wang, F., Lei, M., and Lue, N.F. A proposed OB-fold structure with a protein-interaction surface in the Candida albicans telomerase protein Est3. Nat. Struc. Mol. Biol., 15: 985-989 (2008).
• Lue, N.F. Closing the feedback loop: how cells count telomere bound proteins. Mol. Cell, 33: 413-414 (2009).
• Lue, N.F. The plasticity of telomere maintenance mechanisms in yeast. Trends Biochem. Sci., in press.
