Appointments
 
Associate Professor of Pharmacology

 
Weill Cornell \r\nPhysician
   

Levin, Lonny R.
 (212) 746-6752  (212) 746-6241

Dr. Levin has been studying the cAMP signaling pathway for over 20 years and adenylyl cyclases for over 15. As a Graduate Student in the Laboratory of Dr. Mark J. Zoller at Cold Spring Harbor Laboratory, he used molecular genetics and biochemistry to study the regulation of Protein Kinase A, the predominant cAMP effector protein in cells. As a Post-doctoral Fellow in the laboratory of Dr. Randall R. Reed at Johns Hopkins School of Medicine, he cloned and characterized the first Drosophila adenylyl cyclase. As a member of the Pharmacology Department of Weill Cornell Medical College, he first continued his studies identifying and characterizing Drosophila adenylyl cyclase genes. Then in 1998, he collaborated with Dr. Buck to identify, clone, and biochemically characterize a novel form of adenylyl cyclase in mammals, the soluble adenylyl cyclase (sAC). He and Dr. Buck remain collaborators studying the biochemistry and biology of mammalian sAC. They have combined their laboratories into a combined research program studying bicarbonate/carbon dioxide chemosensing via the second messenger cAMP.

 


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