Stirrett K.L., Ferreras J.A., Sinha B., Venkatesan J., Ren T., and Quadri L.E.N. (2008). Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. Bioorg. Med. Chem. Lett. 18:2662-2668. On-line at http://dx.doi.org/10.1016/j.bmcl.2008.03.025
Ferreras A.J., Stirrett K.L., Lu X., Ryu, J.S., Soll C.E., Tan D.S. and Quadri L.E.N. (2008). Mycobacterial phenolic glycolipid virulence factor biosynthesis: mechanism and small-molecule inhibition of polyketide chain initiation. Chem. Biol. 15:51-61. Online: 12/27/07. -- [Highlighted in the January issue of Start-Up, article ID 2008900019.]
Quadri L.E.N (2008). Iron uptake by Mycobacterium tuberculosis. In: Handbook of Tuberculosis: Molecular Biology and Biochemistry. Eds: S Kaufman and E Rubin. WILEY-VCH Verlag GmbH & Co. KgaA, Weinheim. pp 91-110.
Crick D., Quadri L.E.N., and Brennan P. (2008). Biochemistry of the Cell Envelope of Mycobacterium tuberculosis. In: Handbook of Tuberculosis: Molecular Biology and Biochemistry. Eds: S Kaufman and E Rubin. WILEY-VCH Verlag GmbH & Co. KgaA, Weinheim. pp 1-20.
Quadri L.E.N. (2008). Iron uptake in mycobacteria. In: The Mycobacterial Cell Envelope. Eds: M Daffe, J-M Reyrat. ASM Press, Washington, DC. pp. 167-184.
Quadri L.E.N. (2007). Strategic paradigm shifts in the antimicrobial drug discovery process of the 21st century. Infect. Disord. Drug Targets 7:230-237. Free on-line at http://www.ingentaconnect.com/content/ben/iddt/2007/00000007/00000003/art00004?token=005519fa021f12dba41333c4a2f24416a592c4046737d70253e4f6d6222346b6268763050210f28567652
Cisar J.S., Ferreras J.A., Soni K.R., Quadri L.E.N., and Tan D.S. (2007). Exploiting ligand conformation in the selective inhibition of non-ribosomal peptide synthetase amino acid adenylation with designed macrocyclic small molecules. J. Am. Chem. Soc. 129:7752-7753. -- [Highlighted in Faculty of 1000: http://www.f1000biology.com/article/id/1087363.]
Rohde B.H. and Quadri L.E.N. (2006). Functional characterization of a three-component regulatory system involved in quorum sensing-based regulation of peptide antibiotic production in Carnobacterium maltaromaticum. BMC Microbiol. 6:96.
Ferreras J.A., Ryu J.S., Di Lello F., Tan D.S., and Quadri L.E.N. (2005). Small molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis. Nature Chem. Biol. 1:29-32. -- [Highlighted in the Research Highlights section of Nature, 2005, 435:389 and in the News of the Week section of Chemical. & Eng. News, 2005, 83:13.]
Onwueme K.C., Vos J.C., Zurita J., Ferreras J.A., and Quadri L.E.N. (2005). The dimycocerosate ester polyketide virulence factors of mycobacteria. Prog. Lipid Res. 44:259-302.
Onwueme K.C., Vos C.J., Zurita J., Soll C.E., and Quadri L.E.N. (2005). Identification of phthiodiolone ketoreductase, an enzyme required for production of mycobacterial diacyl phthiocerol virulence factors. J. Bacteriol. 187:4760-4766.
Palma M., Zurita J., Ferreras J.A., Worgall S., Shi L., Campagne F., and Quadri L.E.N. (2005). Pseudomonas aeruginosa SoxR does not conform to the archetypal paradigm for SoxR-dependent regulation of the bacterial oxidative stress adaptive response. Infect. Immun. 73:2958-2966.
Worgall S., Heguy A., Luettich K., O'Connor T.P., Harvey B.G., Quadri L.E.N., and Crystal R.G. (2005). Similarity of patterns in gene expression of human alveolar macrophages evoked by Pseudomonas aeruginosa and Burkholderia cepacia. Infect. Immun. 73:5262-5268.
Quadri L.E.N. and C. Ratledge. (2005). Iron metabolism in the tubercle bacillus and other mycobacteria. In Tuberculosis and the Tubercle Bacillus. Eds: D.N. McMurray, K. Eisenach, B. Gicquel and W.R. Jacobs, Jr. ASM Press, Washington, DC. p. 341-357.
Onwueme K.C., Ferreras J.A., Buglino J., Lima C.D., and Quadri L.E.N. (2004). Mycobacterial polyketide associated proteins are acyltransferases: Proof of principle with Mycobacterium tuberculosis PapA5, a protein involved in synthesis of virulence-enhancing polyketides. Proc. Natl. Acad. Sci. U. S. A. 101:4608-4613.
Buglino J., Onwueme K.C., Ferreras J.A., Quadri L.E.N., and Lima C.D., (2004). Crystal structure of
PapA5, the phthiocerol dimycocerosyl transferase from Mycobacterium tuberculosis. J. Biol. Chem. 279:30634-30642.
Palma M., Worgall S., Deluca D., and Quadri L.E.N. (2004). Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide. J. Bacteriol. 186:248-252.
Quadri L.E.N. (2003). Regulation of Class II bacteriocin production by cell-cell signaling. J. Microbiol. 41:175-182.
Palma M., Worgall S., and Quadri L.E.N. (2003). Transcriptome analysis of the Pseudomonas aeruginosa response to iron. Arc. Microbiol. 180:374-379.
Quadri L.E.N. (2002). Regulation of antimicrobial peptide production by autoinducer-mediated quorum sensing in lactic acid bacteria. Antonie van Leeuwenhoek 82:133-145.
Kleerebezem M., Kuipers O.K., de Vos W.M., Stiles M. E., and Quadri L.E.N. (2001). A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter. Peptides 22:1597-1601.
Kleerebezem M. and Quadri L.E.N. (2001). Peptide pheromone-dependent regulation of antimicrobial peptide production in Gram-positive bacteria: a case of multicellular behavior. Peptides 22:1579-1596.
Quadri L.E.N. (2000). Assembly of aryl-capped siderophores by modular peptide synthetases and polyketide synthases. Mol. Microbiol. 37:1-12.
Quadri L.E.N., Keating T.A., Patel H.M., and Walsh C.T. (1999). Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin: reconstitution of aryl-4,2-bis-thiazoline synthetase activity from PchD, PchE and PchF. Biochemistry 38:14941-14954.
Franz C.M., Worobo R.W., Quadri L.E.N., Schillinger U., Holzapfel W.H., Vederas J.C., and Stiles M.E. (1999). Atypical genetic locus for enterocin B production in Enterococcus faecium BFE 900. Appl. Environ. Microbiol. 65:2170-2178.
Quadri L.E.N., Sello J., Keating T.A., Weinreb P.H., and Walsh C.T. (1998). Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin. Chem. Biol. 5:631-645.
Quadri L.E.N., Weinreb P.H., Lei M, Nakano M.M., Zuber P, and Walsh C.T. (1998). Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases. Biochemistry 37:1585-1595.
Weinreb P.H., Quadri L.E.N., Walsh C.T., and Zuber P. (1998). Stoichiometry and specificity of in vitro phosphopantetheinylation and aminoacylation of the valine-activating module of surfactin synthetase. Biochemistry 37:1575-1584.
Walsh C.T., Gehring A.M., Weinreb P.H., Quadri L.E.N., and Flugel R.S. (1997). Post-translational modification of polyketide and nonribosomal peptide synthases. Curr. Opin. Chem. Biol. 1:309-315.
Quadri L.E.N., Kleerebezem M, Kuipers O.P., de Vos W.M., Roy K.L., Vederas J.C., and Stiles M.E. (1997). Characterization of a locus from Carnobacterium piscicola LV17B involved in bacteriocin production and immunity: evidence for global inducer-mediated transcriptional regulation. J. Bacteriol. 179:6163-6171.
Kleerebezem M., Quadri L.E.N., Kuipers O.P., de Vos W.M. (1997). Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria. Mol. Microbiol. 24:895-904.
Quadri L.E.N., Yan L.Z., Stiles M.E., Vederas J.C. (1997). Effect of amino acid substitutions on the activity of carnobacteriocin B2. Overproduction of the antimicrobial peptide, its engineered variants, and its precursor in Escherichia coli. J. Biol. Chem. 272:3384-3388.
Quadri L.E.N., Sailer M., Terebiznik M.R., Roy K.L., Vederas J.C., and Stiles M.E. (1995). Characterization of the protein conferring immunity to the antimicrobial peptide carnobacteriocin B2 and expression of carnobacteriocins B2 and BM1. J. Bacteriol. 177:1144-1151.
Quadri L.E.N., Sailer M., Roy K.L., Vederas J.C., Stiles M.E. (1994). Chemical and genetic characterization of bacteriocins produced by Carnobacterium piscicola LV17B. J. Biol. Chem. 269:12204-12211.
Quadri L.E.N., and Giulietti A.M. (1993). Effect of elicitation on the accumulation of solasodine by immobilized cells of Solanum eleagnifolium Cav. Enz. Microb. Technol. 15:1074-1077.

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