Publications
R.S.Veazey, R.J.Shattock, M.Pope, J.C.Kirijan, J.Jones, Q.Hu, T.Ketas, P.A.Marx, P.J.Klasse, D.R.Burton and J.P.Moore. (2003). Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nat.Med. 9, 343-346.
R.S.Veazey, P.J.Klasse, T.A.Ketas, J.Reeves, M.Piatak Jr., K.Kunstman, S.E.Kuhmann, P.A.Marx, J.D.Lifson, J.Dufour, M.Mefford, I.Pandrea, S.M.Wolinsky, R.W.Doms, J.A.DeMartino, S.J.Siciliano, K.Lyons, M.S.Springer and J.P.Moore. (2003). Use of a small-molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection and prevent simian-human immunodeficiency virus infection. J.Exp.Med. 198, 1551-1562.
S.E.Kuhmann, P.A.Pugach, K.Kunstman, J.Taylor, R.Stansfield, A.Snyder, J.M.Strizki, J.Riley, B.M.Baroudy, I.A.Wilson, B.T.Korber, S.M.Wolinsky and J.P.Moore. (2004). Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small molecule CCR5 inhibitor. J.Virol. 78, 2790-2807.
P.Pugach, S.E.Kuhmann, J.Taylor, A.J.Marozsan, A.Snyder, T.Ketas, S.M.Wolinsky, B.T.Korber and J.P.Moore. (2004). The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4. Virology 321, 8-22.
E.Billick, C.Seibert, P.Pugach, T.Ketas, A.Trkola, M.J.Endres, N.J.Murgolo, E.Coates, G.R.Reyes, B.M.Baroudy, T.P.Sakmar, J.P.Moore and S.E.Kuhmann. (2004). The differential sensitivity of human and rhesus macaque CCR5 to small molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitors. J.Virol. 78, 4134-4144.
J.P.Moore and R.W. Doms. (2003). The entry of entry inhibitors: a fusion of science and medicine. Proc.Natl.Acad.Sci.USA 100, 10598-10602.
R.A.Shattock and J.P.Moore. (2003). Inhibiting HIV-1 sexual transmission. Nat.Rev.Microbiol. 1, 25-34.
J.P.Moore, S.G.Kitchen, P.Pugach and J.A.Zack. (2004). The CCR5 and CXCR4 coreceptors - central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res.Human Retro. 20, 111-126.
