Greenfield J, Howard B, Huang C,Boockvar JA. Endoscopic Endonasal transphenoidal surgery using a skull reference array and laser surface scanning, Minim Invas Neurosurg 2008: 51:1-3

Howard B, Hofstetter C, Wagner P, Lavi E, Boockvar JA Transformation of a low-grade pineal parenchymal tumor to a secondary pineoblastoma, in press, Neuropathology and Applied Neurobiology

Howard B, Boockvar JA. Magnetic Resonace Spectroscopy Traces Neural Progenitor Cells in Vivo. Neurosurgery. 2008 Apr: 62(4):N12

Howard B, Boockvar JA. Brain tumor stem cells: will understanding a new paradigm lead to improved therapies? Expert Rev. Neurotherapeutics 8(4), 159-160 (2008)

Howard BM, Boockvar JA, Dunn IF, Friedlander RM. Pluripotential stem cells from mature somatic cells. Neurosurgery. 2008 Feb; 62 (2): N6-7.

Greenfield J, Ayuso-Sacido A, Panullo S, Schwartz T, Souweiddane M, , Stieg P, Boockvar JA. Use of human neural tissue for the generation of progenitors, Neurosurgery 2008 Jan: 62(1):21-37

Ayuso, A., Greenfield, JP., Roy NS., Schwartz TH., Boockvar, JA. Long-term isolation of adult human brain subventricular zone precursors, in press, Neurosurgery , 2008 Jan: 62(1):223-9.

Wong K, Ayuso-Sacido A, Anhow P, Boockvar JA and Wu M. Assessing neural stem cell motility using an agarose gel based microfluidic device, Journal of Visualized Experiments, Vol 1, 2008

Bleau A, Howard, B, Taylor L, Gursel D, Tung L, Greenfield, J, Holland EC, Boockvar, JA. A new strategy for analysis of phenotypic marker antigens in murine and human brain tumor derived neurospheres, , Neurosurg Focus, 24 1-9, March/April 2008

Parikh K, Tomasino A, Knopman J, Boockvar JA, Hartl R. Operative Results and Learning Curve with Microscope-Assisted Tubular Microsurgery for one and two discectomies and laminectomy. In press, Neurosurg Focus, 2008

Ayuso, A., Graham, C., Kratovic, S., Kapoor, G., O?Rourke, D., Roy, N., Boockvar, JA. Activated EGFR signaling induces tumorigenic features in postnatal neural stem cells (in press)

Fraser, J., Boockvar, JA. Intervertebral Disc Transplantation: Treatment in Motion. Neurology Alert, 2007

Ayuso, A., Graham, C., Kratovic, S., Kapoor, G., Holland, E., O?Rourke, D. , Boockvar, JA. Activated EGFR signaling confers an aggressive phenotype to post natal neural stem cells. (submitted for publication)

Fraser, J., Hartl, R., Boockvar, JA. SPORTing Statistics: Slicing the Drive on Appropriate Treatment. Neurology Alert, 2006

Ayuso, A., Graham, C.,Greenfield JP., Boockvar, JA. The duality of EGFR signaling and neural stem cell phenotype: Cell enhancer or cell transformer? Current Stem Cell Research and Therapy, 1, 231-238, 2006

Boockvar JA, Schouten J, Royo N, Millard M, Spangler Z, Castelbuono D, Snyder E, O?Rourke D, McIntosh T. Experimental traumatic brain injury modulates the survival, migratory and terminal phenotype of transplanted EGFR activated neural stem cells Neurosurgery 56: 163-71, 2005

Boockvar JA, Stiefel M, Malhotra N, Dolinskas C, Dwyer-Joyce C, LeRoux PD. Dural Cavernous angioma of the posterior sagittal sinus: case report.
Surgical Neurology 63: 178-181, 2005

Boockvar JA, Kapitonov D, Schouten J, Counelis GJ, Kapoor G, Bogler O, Snyder E, McIntosh T, O?Rourke DM. Constitutive EGFR signaling confers a motile phenotype to neural stem cells. Molecular and Cellular Neuroscience 24, (4): 1116-1130, 2003

Yip S, Aboody KS, Burns M, Imitola J, Boockvar JA, Allport J, Park KI, Teng YD, Lachyankar M, McIntosh T, O'Rourke DM, Khoury S, Weissleder R, Black PM, Weiss W, Snyder EY. Neural stem cell biology may be well suited for improving brain tumor therapies. Cancer J 9(3):189-204, 2003

Riess P, Zhang C, Saatman K, Laurer HL, Teng T, Bareyre FM, Raghupathi R, Lenzlinger P, Longhi L, Lifshitz J, Neugebauer E, Boockvar JA, Snyder E, McIntosh TK. Transplanted neural stem cells survive, differentiate and improve neurologic motor function after experimental traumatic brain injury. Neurosurgery 51 (4): 1-11, 2002

Boockvar JA, Durham S, Sun P. Congenital cervical spinal stenosis and sports-related cervical cord neurapraxia in children. Spine 26 (24): 2709-2712, 2001

Boockvar JA, Loudon W, Sutton LN. The development of the Spitz-Holter valve in Philadelphia. Journal of Neurosurgery 95: 145-147, 2001

Boockvar JA, Zager EL: Surgical management of cubital tunnel syndrome. In Thieme?s (ed): Seminars in Neurosurgery, Vol. 12 (1): 57-63, 2001

Boockvar JA, Phillips MF, Telfeian AE, O?Rourke D, Marcotte PJ. Results and risk factors for anterior cervicothoracic junction surgery. Journal of Neurosurgery Spine 94: 12-17, 2001

Boockvar JA, Telfeian AE, Baltuch GH, Skolnick B, Simuni T, Stern M, Schmidt L, Trojanowski JQ.: Long-term deep brain stimulation in a patient with essential Tremor: clinical response and postmortem correlation with stimulator termination sites in ventral thalamus. Journal of Neurosurgery 93: 140-144, 2000

Telfeian AE, Boockvar JA, Simuni T, Jaggi J, Skolnick B, Baltuch GH: Efficacy of unilateral deep brain stimulation of the VIM nucleus of the thalamus in a patient with bipolar disorder associated with Klinefelter?s syndrome and essential tremor. Journal of Neurosurgery 93: 127-128, 2000

Boockvar JA, Shafa B, Forman M, O?Rourke D.: Symptomatic lateral ventricular ependymal cysts: Criteria for distinguishing these rare cysts from other symptomatic cysts of the ventricles. Case Report. Neurosurgery 46(5): 1229-1233, 2000

Boockvar JA, Virella A, Kotapka M, Flamm ES, Grady MS.: Neurosurgery at the University of Pennsylvania Medical Center. Neurosurgery 46 (5): 1223-1228, 2000

Boockvar JA, Kotzen RA, Swanson R, Milhorat TH.: Post-traumatic meningioma: case report and historical perspective. J Neurol Neurosurg Psych 66: 796-798, 1999

Boockvar JA, Black K, Malik S, Stanek A, Tracey KJ.: Subacute paraparesis induced by venous thrombosis of a spinal angiolipoma. Spine 22:2304-2308, 1997

Manuscripts in preparation:

Kapitonov D, Boockvar JA, O?Rourke DM. Mechanisms of EGFRvIII transactivation and signaling in C17.2 mouse neural stem cells. (in preparation)

Boockvar JA, Gwertzman G, Loureiro M, Scicutello T, Zenetos P. SB Charite Lumbar artificial disc placement in a patient with previous abdomino-pelvic surgery: Technical note. (Submitted)

Boockvar JA, Huang J, O?Rourke DM. Post-operative cervical instability following multi-level cervical laminectomy for cervical spondylotic myelopathy (in preparation)


Books, Book Chapters and Reviews

Fraser, J, Boockvar JA, Hartl R: Traumatic Spinal Injury. Barrie (ed): Trauma Surgery, 2006

Boockvar JA, LeRoux P: Meningeal Neoplasms with Aggressive Behavior. In Wilken?s and Rengencary (ed): Neurosurgery (3rd edition). Lippencott, Williams and Wilkens, Baltimore, 2003

Boockvar JA, Judy K.: Surgery for hemispheric gliomas. In Stein S (ed): Neurobase: Surgical Edition. San Diego: Arbor Publishing Corp, 1999

Published Commentaries:

Boockvar, JA. California Stem Cell Initiative. Science Times, Neurosurgery, Vol. 56: 1, N7, 2005

Boockvar, JA. Autologous Adipose-derived Stem Cells and Fibrin Glue Used to Treat Widespread Traumatic Calvarial Defects. Science Times, Neurosurgery, Vol. 56: 3, N9, 2005

Boockvar, JA. Bone marrow derived stem cells for boney fusion. Science Times, Neurosurgery, Vol. 56: 3, N9, 2005

Ayuso, A. Boockvar, JA. Allodynia limits the usefulness of intraspinal neural stem cell grafts. Science Times, Neurosurgery, Vol. 56: 3, N9, 2005

Greenfield, J. Boockvar, JA. Patient derived embryonic stem cells. Science Times, Neurosurgery, Vol. 57: 4, N9, 2005

Greenfield, J. Boockvar, JA. Is there a Glioma Stem Cell? Science Times, Neurosurgery, Vol. 57: 6, N7, 2005

Boockvar, JA. Hair follicle stem cells support repair of severed peripheral nerves, Neurosurgery, Vol. 58: 2, N9 2006

Greenfield J, Boockvar, JA. Fallibility of GBM cell lines overcome by use of tumor derived stem cell lines, Neurosurgery Vol 59: 2, N9 2006

Greenfield J, Boockvar, JA. Neurocytoma Is a Tumor of Adult Neuronal Progenitor Cells Vol 60: 2, 8N9 2007

Greenfield J, Boockvar, JA. Repairing Damage within the Subventricular Zone Neurosurgery Vol 60: 4 N6 2007

Selected Invited Lectures and Ground Rounds Presenatations within last two years

Boockvar, JA. Stem cells and CNS malignancies, Endocrinology Grand Rounds, Weill Cornell Medical College, May, 2007

Boockvar, JA. Molecular determinants of GBM and rationale for treatment, Neurology Grand Rounds, Weill Cornell Medical College, January 2007

Boockvar, JA. Molecular determinants of GBM and rationale for treatment, Hematology and Oncology Grand Rounds, Weill Cornell Medical College, January 2007

Boockvar, JA. New Treatment Strategies in the Management of Malignant Gliomas, Wyckoff Heights Medical Conference, Brooklyn, NY 2006

Boockvar, JA. Endoscopic Pituitary Surgery. Salzburg Neurosurgery Conference, Salzburg, Austria, 2006 and 2007

Boockvar, JA. Minimally Invasive Spinal Fusion. Salzburg Neurosurgery Conference, Salzburg, Austria, 2006 and 2007

Boockvar, JA. Neurotransplantation. Future Limits. World Congress of Neurological Surgeons, Marrakesh, Morocco, 2005

Boockvar, JA. Minimally Invasive Spinal Fusion. Congress of Neurological Surgery, Boston MA, 2005

Selected recent abstracts

Erlotinib, a small molecule Epidermal Growth Factor Receptor (EGFR) inhibitor, does not cause direct cytotoxicity to rodent na?ve brain following its administration by Convection-Enhanced Delivery: Implications for Glioma Therapy . Ionnis, Boockvar JA, Soweiddane M, Society for Neuro-oncology, Orlando, 2007

Cytotoxicity of Statins on Glioblastoma cells with varying levels of EGFR signaling. Cheng C, Dattatreyudu N, Li G, Ayuso-Sacido A, Boockvar JA. Society for Neuro-oncology, Orlando, 2006

Ayuso-Sacido A, Kapitonov D, Graham C, Ahmad FS, and Boockvar JA. Characterization of a new cell based system to evaluate the EGFR signaling influence in neural stem cells phenotype determination. ISSCR, Toronto 2006

Ayuso-Sacido A, Kapitonov D, Graham C, Ahmad FS, and Boockvar JA. Development of an adult human neural stem cell bank. AANS, San Francisco, 2006

Wells Roth D, Hartl R, Boockvar JA. Minimally invasive spinal fusion with unilateral pedicle screw fixation for single level degenerative spine disease. AANS, San Francisco, 2006

Boockvar JA, Schouten J, Shimuzo S, Millard M, Patel M, Hoover R, Snyder E,
O?Rourke D, McIntosh TK. Activated EGFR signaling and transplanted neural stem cell motility. Journal of Neurotrauma 19 (10): 1276, 2002

Boockvar JA, Counelis G, Kapitonov D, Bogler O, Shouten J, Grady MS, McIntosh T, O?Rourke, D. Constitutive EGFRvIII signaling and neural stem cell phenotype. The Congress of Neurosurgeons, Philadelphia, PA September 2002

Boockvar JA, Counelis G, Bogler O, O?Rourke DM. Cooperative signaling between EGFR and myc in modulating neural stem cell phenotype. The American Association of Neurological Surgeons, Section on Tumors, Chicago, Illinois, April 2002

Boockvar JA, Bogler O, Kapitonov D, Ma L, O?Rourke DM. Alteration of EGFR signaling and neural stem cell phenotype. The American Association of Neurological Surgeons, Chicago, Illinois, April 2002

Boockvar JA, Bogler O, Kapitonov D, Ma L, O?Rourke DM. EGFR signaling affects fate choices and neural stem cell phenotype. Developmental Brain Research 134 (2002) A14

Boockvar JA. Neural stem cells: A strategy for gene therapy and CNS repair. Philadelphia Neurological Society, Philadelphia, PA, March 2001

Boockvar JA, Durham S, Sun P. Congenital cervical spinal stenosis and sports-related cervical cord neurapraxia in children. The AANS/CNS Section on Pediatric Neurological Surgery, San Diego, CA, December 2000

Boockvar JA. Post-Traumatic meningioma: Current controversy and historical perspective. The American Association of Neurological Surgeons, Philadelphia, PA, April 1998.

Boockvar JA, Murthy J, Ivanova S, Meistrell M, Botchkina G, Tracey KJ. Brain TNF production mediated by the cytotoxin 3-aminopropanal. The American Association of Neurological Surgeons, Denver, Colorado, April 1997.

Editorial Boards:

Current Stem Cell Research and Therapeutics, 2005-present
Recent Patents on Anti-Cancer Drug Discovery, 2005-present

Ad hoc Reviewer: Neurosurgery, Brain Research, Human Gene Therapy


If you would like to make an appointment with Dr. Boockvar, please call 212-746-1996.

For more information about our Brain Tumor Center, please visit us at www.cornellneurosurgery.org/braintumor.

For more information on Brain Tumors, please visit the following sites:

New York Brain Tumor Center

Brain Tumor Research Group