Pena A, Murat B, Trueba M, Ventura MA, Bertrand G, Cheng LL, Stoev S, Szeto HH, Wo N, Brossard G, Serradeil-Le Gal C, Manning M, Guillon G. Pharmacological and physiological characterization of d[Leu4, Lys8]vasopressin, the first V1b-selective agonist for rat vasopressin/oxytocin receptors. Endocrinology. 2007 Sep;148(9):4136-46. Epub 2007 May 10. PMID: 17495006
Cho J, Won K, Wu D, Soong Y, Liu S, Szeto HH, Hong MK. Potent mitochondria-targeted peptides reduce myocardial infarction in rats. Coron Artery Dis. 2007 May;18(3):215-20. PMID: 17429296
Pena A, Murat B, Trueba M, Ventura MA, Wo NC, Szeto HH, Cheng LL, Stoev S, Guillon G, Manning M. Design and synthesis of the first selective agonists for the rat vasopressin V(1b) receptor: based on modifications of deamino-[Cys1]arginine vasopressin at positions 4 and 8. J Med Chem. 2007 Feb 22;50(4):835-47. PMID: 17300166
Cho S, Szeto HH, Kim E, Kim H, Tolhurst AT, Pinto JT. A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36. J Biol Chem. 2007 Feb 16;282(7):4634-42. Epub 2006 Dec 18. PMID: 17178711
Thomas DA, Stauffer C, Zhao K, Yang H, Sharma VK, Szeto HH, Suthanthiran M. Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function. J Am Soc Nephrol. 2007 Jan;18(1):213-22. Epub 2006 Dec 6. PMID: 17151329
Szeto HH. Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J. 2006 Aug 18;8(3):E521-31. Review. PMID: 17025271
Petri S, Kiaei M, Damiano M, Hiller A, Wille E, Manfredi G, Calingasan NY, Szeto HH, Beal MF. Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis. J Neurochem. 2006 Aug;98(4):1141-8. PMID: 16895581
Stoev S, Cheng LL, Manning M, Wo NC, Szeto HH. Design and synthesis of potent, highly selective vasopressin hypotensive agonists. J Pept Sci. 2006 Sep;12(9):592-604. PMID: 16625682
Zhao K, Luo G, Giannelli S, Szeto HH. Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines. Biochem Pharmacol. 2005 Dec 5;70(12):1796-806. Epub 2005 Oct 10. PMID: 16216225
Guillon G, Pena A, Murat B, Derick S, Trueba M, Ventura MA, Szeto HH, Wo N, Stoev S, Cheng LL, Manning M. Position 4 analogues of [deamino-Cys(1)] arginine vasopressin exhibit striking species differences for human and rat V(2)/V(1b) receptor selectivity. J Pept Sci. 2006 Mar;12(3):190-8. PMID: 16130178
Manning M, Cheng LL, Stoev S, Wo NC, Chan WY, Szeto HH, Durroux T, Mouillac B, Barberis C. Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosiban. J Pept Sci. 2005 Oct;11(10):593-608. PMID: 15880385
Shimoyama M, Kuwaki T, Nakamura A, Fukuda Y, Shimoyama N, Schiller PW, SSzeto HH. Differential respiratory effects of [Dmt1]DALDA and morphine in mice. Eur J Pharmacol. 2005 Mar 28;511(2-3):199-206. PMID: 15792789
Szeto HH, Schiller PW, Zhao K, Luo G. Fluorescent dyes alter intracellular targeting and function of cell-penetrating tetrapeptides. FASEB J. 2005 Jan;19(1):118-20. Epub 2004 Oct 15. PMID: 15489247
Gomes I, Gupta A, Filipovska J, Szeto HH, Pintar JE, Devi LA. A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia. Proc Natl Acad Sci U S A. 101(14):5135-9, 2004.
Wan H, Umstot ES, Szeto HH, Schiller PW, Desiderio DM. Quantitative analysis of [Dmt(1)]DALDA in ovine plasma by capillary liquid chromatography-nanospray ion-trap mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 803(1):83-90, 2004. Other Publications
Education
Ph.D.,
Weill Cornell Graduate School of Medical Sciences,
1977
M.D.,
Cornell University Medical College, NY,
1977
B.S.,
Indiana University,
1972
Appointments
Professor of Pharmacology Weill Cornell Medical College