Hemmings HC Jr, Flood P. Galloping in full pursuit of the mechanism of anesthetic immobility. Anesthesiology. 2008 Jun;108(6):975-6.
PMID: 18497595

Platholi J, Heerdt PM, Lim Tung HY, Hemmings HC Jr. Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma. J Neurochem. 2008 Jun;105(5):2029-38. Epub 2008 Feb 14.
PMID: 18284617

Zhang TT, Platholi J, Heerdt PM, Hemmings HC Jr, Tung HY. Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation. Metab Brain Dis. 2008 Mar;23(1):95-104. Epub 2008 Jan 16.
PMID: 18197471

Hemmings HC Jr. Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor. Anesthesiology. 2007 Nov;107(5):694-6.
PMID: 18073542

Westphalen RI, Krivitski M, Amarosa A, Guy N, Hemmings HC Jr. Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1. Br J Pharmacol. 2007 Nov;152(6):939-45. Epub 2007 Sep 10.
PMID: 17828284

Snyder GL, Galdi S, Hendrick JP, Hemmings HC Jr. General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo. Neuropharmacology. 2007 Oct;53(5):619-30. Epub 2007 Jul 24.
PMID: 17826804

OuYang W, Hemmings HC Jr. Isoform-selective effects of isoflurane on voltage-gated Na+ channels. Anesthesiology. 2007 Jul;107(1):91-8.
PMID: 17585220

Ouyang W, Jih TY, Zhang TT, Correa AM, Hemmings HC Jr. Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel. J Pharmacol Exp Ther. 2007 Sep;322(3):1076-83. Epub 2007 Jun 14.
PMID: 17569823

Bullock SA, Platholi J, Gjyrezi A, Heerdt PM, Tung HY, Hemmings HC Jr. Differential regulation of protein phosphatase-1(I) by neurabin. Biochem Biophys Res Commun. 2007 Jun 22;358(1):140-4. Epub 2007 Apr 19.
PMID: 17467665

Nguyen C, Nishi A, Kansy JW, Fernandez J, Hayashi K, Gillardon F, Hemmings HC Jr, Nairn AC, Bibb JA. Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5. J Biol Chem. 2007 Jun 1;282(22):16511-20. Epub 2007 Mar 30.
PMID: 17400554

Hotte M, Thuault S, Dineley KT, Hemmings HC Jr, Nairn AC, Jay TM. Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo. Synapse. 2007 Jan;61(1):24-8.
PMID: 17068779

Bruening S, Oh E, Hetzenauer A, Escobar-Alvarez S, Westphalen RI, Hemmings HC Jr, Singewald N, Shippenberg T, Toth M. The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system. J Neurochem. 2006 Nov;99(3):892-9. Epub 2006 Aug 21.
PMID: 16925594

Hemmings HC Jr, Antognini JF. Do general anesthetics add up? Anesthesiology. 2006 Jun;104(6):1120-2.
PMID: 16732079

Hotte M, Thuault S, Lachaise F, Dineley KT, Hemmings HC, Nairn AC, Jay TM. D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex. Behav Brain Res. 2006 Jul 15;171(1):127-33. Epub 2006 May 9.
PMID: 16687181

Westphalen RI, Hemmings HC Jr. Volatile Anesthetic Effects on Glutamate versus GABA Release from Isolated Rat Cortical Nerve Terminals: Basal Release.
J Pharmacol Exp Ther. 2006 Jan;316(1):208-15.

Westphalen RI, Hemmings HC Jr. Volatile Anesthetic Effects on Glutamate versus GABA Release from Isolated Rat Cortical Nerve Terminals: 4-Aminopyridine-Evoked Release. J Pharmacol Exp Ther. 2006 Jan;316(1):216-23.

Hemmings HC Jr, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL. Emerging molecular mechanisms of general anesthetic action. Trends Pharmacol Sci. 2005 Oct;26(10):503-10. Review.

Foundations of Anesthesia: Basic Sciences for Clinical Practice 2e, HC Hemmings Jr, PM Hopkins, eds (2006; Mosby Elsevier, London).

Hemmings HCJr, Yan W, Westphalen RI, Ryan TA (2005) The general anesthetic isoflurane depresses synaptic vesicle exocytosis. Mol Pharmacol 67:1591-9.

Fu D, Vissavajjhala P, Hemmings HC Jr. (2005) Volatile anaesthetic effects on phospholipid binding to synaptotagmin 1, a presynaptic Ca2+ sensor. Br J Anaesth. 95:216-21.

Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC Jr, Nishi A, Greengard P, Nairn AC. (2005) Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5). Proc Natl Acad Sci USA 102:3489-94.

OuYang W, Wang G, Hemmings HC Jr. (2004) Distinct rat neurohypophysial nerve terminal populations identified by size, electrophysiological properties and neuropeptide content. Brain Res. 1024:203-11.

Ouyang W, Hemmings HC Jr. (2004) Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals. J Pharmacol Exp Ther. 312:801-8.

Morrow PW, Tung HY, Hemmings HC Jr. (2004) Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells. Biochem Biophys Res Commun. 323:645-51.

Balint E, Kitka T, Zachar G, Adam A, Hemmings HC Jr, Csillag A. (2004)Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks. J Chem Neuroanat. 28:27-36.

Hemmings HC Jr. (2004) Neuroprotection by Na+ channel blockade. J Neurosurg anesthesiol. 16:100-1. Review.

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