Roepke TK, Kontogeorgis A, Ovanez C, Xu X, Young JB, Purtell K, Goldstein PA, Christini DJ, Peters NS, Akar FG, Gutstein DE, Lerner DJ, Abbott GW. Targeted deletion of kcne2 impairs ventricular repolarization via disruption of IK,slow1 and Ito,f. FASEB J. 2008 Jul 4. [Epub ahead of print]
PMID: 18603586

Panaghie G, Purtell K, Tai KK, Abbott GW. Voltage-dependent C-type inactivation in a constitutively open K+ channel. Biophys J. 2008 Jun 20. [Epub ahead of print]
PMID: 18567635

Morrey C, Estephan R, Abbott GW, Levi R. Cardioprotective Effect of Histamine H3-Receptor Activation: Pivotal Role of G{beta}{gamma}-Dependent Inhibition of Voltage-Operated Ca2+ Channels. J Pharmacol Exp Ther. 2008 Jun 3. [Epub ahead of print]
PMID: 18523159

Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature. 2008 May 22;453(7194):524-8. Epub 2008 Apr 23.
PMID: 18432194

Abbott GW, Ramesh B, Srai SK. Secondary structure of the MiRP1 (KCNE2) potassium channel ancillary subunit. Protein Pept Lett. 2008;15(1):63-75.
PMID: 18221016

Gordon E, Panaghie G, Deng L, Bee KJ, Roepke TK, Krogh-Madsen T, Christini DJ, Ostrer H, Basson CT, Chung W, Abbott GW. A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance. Cardiovasc Res. 2008 Jan;77(1):98-106. Epub 2007 Oct 4.
PMID: 18006462

Abbott GW, Xu X, Roepke TK. Impact of ancillary subunits on ventricular repolarization. J Electrocardiol. 2007 Nov-Dec;40(6 Suppl):S42-6.
PMID: 17993327

Choi E, Abbott GW. The MiRP2-Kv3.4 potassium channel: muscling in on Alzheimer's disease. Mol Pharmacol. 2007 Sep;72(3):499-501. Epub 2007 Jun 26.
PMID: 17595326

Panaghie G, Abbott GW. The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes. J Gen Physiol. 2007 Feb;129(2):121-33. Epub 2007 Jan 16.
PMID: 17227916

Abbott G.W. & Roepke, T.K. Pharmacogenetics of drug-induced arrhythmias. Expert Review of Clinical Pharmacology (in press), 2007

Roepke, T.K., Anantharam, A., Kirchhoff, P., Busque, S.M., Young, J.B., Geibel, J.P., Lerner, D.J., & Abbott G.W. The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion. Journal of Biological Chemistry 281 (33): 23740-23747, 2006

Gordon, E., Cohen, J.L., Engel, R, & Abbott G.W. 1,4-diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers. Molecular Pharmacology 69(3):718-726, 2006

Panaghie, G., Tai, K.K., & Abbott G.W. Interaction of KCNE subunits with the KCNQ1 K+ channel pore. Journal of Physiology 570 (Pt 3):455-67, 2006

Gordon, E., Roepke, T.K., & Abbott G.W. Endogenous MinK-Related Peptides Govern the Activation Kinetics of Kv2.1 Potassium Channels in Xenopus oocyte studies. Biophysical Journal 90(4):1223-31, 2006

Abbott G.W., Butler, M.H., & Goldstein, S.A. Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis. FASEB Journal 20(2):293-301, 2006

Panaghie, G., & Abbott G.W. The impact of ancillary subunits on small-molecule interactions with voltage-gated potassium channels. Current Pharmaceutical Design 12(18): 2285-2302, 2006

Abbott G.W. Molecular mechanisms of cardiac potassium channelopathies. Current Pharmaceutical Design 12(28): 3631-3644, 2006

Roepke, T.K, & Abbott G.W. Pharmacogenetics and cardiac ion channels. Vascular Pharmacology 44(2):90-106, 2006

Cacheaux, L.P., Topf, N., Tibbs, G.R., Schaefer, U.R., Levi, R., Harrison, N.L., Abbott G.W. & Goldstein, P. Impairment of HCN channel function by the intravenous general anesthetic propofol. J. Pharm Exp. Ther. 315(2):517-25, 2005

Anantharam A & Abbott G.W. Does hERG coassemble with a beta subunit? Evidence for roles of MinK and MiRP1 in The hERG Cardiac Potassium Channel: structure, function and drug-induced long QT syndrome. Novartis Foundation, London, U.K., 2005

McCrossan ZA & Abbott G.W. The MinK-Related Peptides Neuropharmacology 47 (6) 787-821, 2004

Gordon E & Abbott G.W. RNAi in Xenopus laevis oocytes in Gene Silencing by RNA Interference: Technology and Application CRC Press, FL, U.S.A., 2004

Lewis A, McCrossan ZA, Abbott G.W. MinK, MiRP1, and MiRP2 diversify Kv3.1 and Kv3.2 potassium channel gating. J Biol Chem. 279(9):7884-92, 2004.

Anantharam A, Markowitz SM, Abbott G.W. Pharmacogenetic considerations in diseases of cardiac ion channels. J Pharmacol Exp Ther. 307(3):831-8, 2003.

McCrossan ZA, Lewis A, Panaghie G, Jordan PN, Christini DJ, Lerner DJ, Abbott G.W. MinK-related peptide 2 modulates Kv2.1 and Kv3.1 potassium channels in mammalian brain. J Neurosci. 23(22):8077-91, 2003.

Tai KK, McCrossan ZA, Abbott G.W. Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death. J Neurochem. 84(5):1193-200, 2003.

Anantharam A, Lewis A, Panaghie G, Gordon E, McCrossan ZA, Lerner DJ, Abbott G.W. RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies. J Biol Chem. 278(14):11739-45, 2003.

Abbott G.W., Goldstein SA. Disease-associated mutations in KCNE potassium channel subunits (MiRPs) reveal promiscuous disruption of multiple currents and conservation of mechanism. FASEB J. 2002 Mar;16(3):390-400, 2002.

Abbott G.W. & Goldstein, S.A.N. The KCNE superfamily of potassium channel subunits: physiology and pathophysiology of the MinK-related peptides (MiRPs). Molecular Interventions 1:95-107, 2001.

Abbott G.W., Goldstein, S.A.N., & Sesti, F. Do all voltage-gated potassium channels employ MiRPs? Circulation Research 88:981-983, 2001.

Abbott G.W., Butler, M.H., Bendahhou, S., Dalakas, M.C., Ptacek, L.J., & Goldstein, S.A.N. MiRP2 forms potassium channels in skeletal muscle with Kv3.4 and is associated with periodic paralysis. Cell 104:217-231, 2001.

Sesti, F., Abbott G.W., Wei, J., Murray, K.T., Saksena, S., Schwartz, P.J., Priori, S.G., Roden, D.M., George, Jr., A.L., & Goldstein, S.A.N. A polymorphism associated with cardiac arrhythmia increases sensitivity to a common antibiotic. Proc. Nat. Acad. Sci. 97:10613-10618, 2000.

Abbott G.W., Sesti, F., Splawski, I., Buck, M.E., Lehmann, M.H., Timothy, K.W., Keating, M.T. & Goldstein, S.A.N. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. Cell 97:175-187, 1999.

Abbott G.W. and Goldstein, S.A.N. A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs). Q. Revs. Biophys. 31, 357-398, 1998

Abbott G.W., Mercer, E.A.J., Miller, R.T., Ramesh, B. & Srai, S.K.S. Conformational changes in a mammalian voltage-dependent potassium channel inactivation peptide. Biochemistry 37 1640-1645, 1998

Mercer, E.A.J., Abbott G.W., Brazier, S., Ramesh, B., Haris, P.I. & Srai, S.K.S. Synthetic putative transmembrane region of minimal potassium channel protein (minK) adopts an alpha-helical conformation in phospholipid membranes. Biochemical Journal 325 (2) 475-9, 1997

Abbott G.W., Bloemendal, M., Van Stokkum, I.H.M., Mercer, E.A.J., Miller, R.T., Sewing, S., Wolters, M., Pongs, O. & Srai, S.K.S. Secondary structure, stability and tetramerisation of recombinant Kv1.1 potassium channel cytoplasmic N-terminal fragment. Biochim. Biophys. Acta 1341 71-78, 1997