Publications
Selected publication
Sung, C-H., Hu, C.-P., Hsu, H.-C., Ng, A. K., Chou, C.-K., Ting, L. P., Su, T.-S., Han, S., and Chang, C. 1989. Expression of class I and class II major histocompatibility antigens on human hepatocellular carcinoma. J. Clin. Invest. 83: 421-429.
Sung, C.-H., Davenport, C. M., Hennessey, J. C., Maumenee, I. H., Jacobson, S. G., Heckenlively, J. R., Nowakowski, R., Fishman, G., Gouras, P., & Nathans, J. 1991. Rhodopsin mutations in autosomal dominant retinitis pigmentosa. Proc. Natl. Acad. Sci. USA 88: 6481-6485.
Sung C.-H., Schneider, B., Agarwal, N., Papermaster, D. S., and Nathans, J. 1991. Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa. Proc. Natl. Acad. Sci. USA 88: 8840-8844.
Jacobson, S. G., Kemp, C. M., Sung, C.-H., and Nathans, J. 1991. Retinal function and rhodopsin levels in autosomal dominant retinitis pigmentosa with rhodopsin mutations. Am. J. Ophthalmol. 112: 256-271.
Kemp, C. M., Jacobson, S. G., Roman, A. J., Sung, C.-H., and Nathans, J. 1992. Abnormal rod dark adaptation in autosomal dominant retinitis pigmentosa with proline-23-histidine rhodopsin mutation. Am. J. Ophthalmol. 113: 165-174.
Nathans, J., Sung, C.-H., Weitz, C. J., Davenport, C. M., Merbs, S. L., and Wang, Y. 1992. Visual pigments and inherited variation in human vision. J. Gen. Physiol.-Sensory Transduction, 110-131.
Sung, C.-H., Davenport C., and Nathans, J. 1993. Rhodopsin mutations responsible for autosomal dominant retinitis pigmentosa: clustering of functional classes along the polypeptide chain. J. Biol. Chem. 268: 26645-26649.
Portera-Cailliau, C., Sung, C.-H., Nathans, J., and Adler, R. 1994. Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc. Natl. Acad. Sci. USA 91: 974-978.
Jacobson, S. G., Kemp, C. M., Cideciyan, A. V., Macke, J. P., Sung, C.-H., and Nathans, J. 1994. Phenotypes of stop codon and splice site rhodopsin mutations causing retinitis pigmentosa. Invest. Ophthal. Vis. Science. 35: 2521-2534.
Sung, C.-H., Makino, C., Baylor, D., and Nathans, J. 1994. A rhodopsin gene mutation responsible for autosomal dominant retinitis pigmentosa results in a protein that is defective in localization to the photoreceptor outer segment. J. Neurosci. 14: 5818-5833.
Kumar, R., Chen, S., Scheurer, D., Duh, E., Sung, C.-H., Rehemtulla, A., Swaroop, A., Adler, R., and Zack, D. J. 1996. The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures. J. Biol. Chem. 2271: 29612-29618.
La Vail, M. M., Yasumura, D., Matthes, M. T., Lau-Villacorta, C., Unoki, K., Sung, C.-H., and Steinberg, R. H. 1998. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest. Ophthal. Vis. Science 39:592-602.
Tai, A. W., J.-Z. Chuang, and C.-H. Sung. 1998. Localization of Tctex-1, a cytoplasmic dynein light chain, to the Golgi apparatus and evidence for dynein complex heterogeneity. J. Biol. Chem. 273: 19639-19649.
Chuang, J.-Z., and C.-H. Sung. 1998. The carboxy-terminus of rhodopsin functions as an apical sorting signal in MDCK cells. J. Cell Biol. 142: 1245-1256.
Chuang, J.-Z., T. A. Milner, M. Zhu, and C.-H. Sung. 1999. A 29 kDa intracellular chloride channel p64H1 is associated with large-dense core vesicles in rat hippocampal neurons. J. Neurosci. 19:2919-2928.
Tai, A. W., J.-Z. Chuang, C. Bode, U. Wolfrum, and C.-H. Sung. 1999. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1. Cell 97: 877-887.
Yano, H. F. Lee, H. Kong, J. C. Arevalo, P. Perez, C.-H. Sung, and M. V. Chao. 2001. Association of a component of the cytoplasmic dynein motor with the Trk neurotrophin receptor. J. Neurosci. 21: RC125(1-7).
Tai, A. W., J.-Z. Chuang, and C.-H. Sung. 2001. Cytoplasmic dynein function is regulated by its subunit composition and is required for the apical translocation of rhodopsin in polarized MDCK cells. J. Cell Biol. 153:1499-1509.
Chuang, J.-Z. T. A. Milner, and C.-H. Sung. 2001. Subunit heterogeneity of cytoplasmic dynein: differential expression of 14-kDa dynein light chains in rat hippocampus. J. Neurosci. 21:5501-5512.
Yamada, H., Yamada, E., Ando, A., Esumi, N., Bora, N., J. Saikia, J., Sung, C.-H., D. Zack,. and Campochiaro, P. A. 2001. Fibroblast growth factor-2 decreases hyperoxia-induced photoreceptor cell death in mice. Am. J. Histopath. 159: 1113-1120.
Chuang, J.-Z., H. Zhou, M. Zhu, S.-H. Li, X.-J. Li, C.-H. Sung. 2002. Characterization of a brain-enriched chaperone, MRJ, that inhibits huntingtin aggregation and toxicity independently. J. Biol. Chem. 277:19831-19838.
Dunaief, J. L., A. King, N. Esumi, M. Eagen, T. Dentchev, C.-H. Sung, S. Chen, and D. J. Zack. 2002. Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo. 2002. Curr. Eye Res. 24:392-396.
Wang. X., S. Xu., C. Rivolta, L. Li, G.-H. Peng, P.-K. Swain, C.-H. Sung, A. Swaroop, E. L. Berson, T. P. Dryja, R. Craigie, and S. Chen. 2002. Barrier to autointegration factor interacts with the cone-rod homeobox and represses its transactivation function. J. Biol. Chem. 277:43288-43300.
Hu Y, J.-Z. Chuang, K. Xu, T. G. McGraw, C.-H. Sung. 2002. SARA, a FYVE domain protein, affects Rab5-mediated endocytosis. 2002. J. Cell Sci. 115:4755-4763.
Chuang, J.-Z., C. Vega, W. Jun, and C.-H. Sung. 2004. Structural and functional impairment of endocytic pathways by retinitis pigmentosa mutant rhodopsin-arrestin complexes. J. Clin. Invest. 114(1):131-140. (COVER)
Yeh, T., J.-Z. Chuang, C.-H. Sung. 2005. Cytoplasmic dynein light chain RP3 is a nuclear matrix associated transcription co-repressor. J. Cell Sci. 118:3431-3443 (COVER).
Chuang, J.-Z., T.-Y Yeh, C. Conde, F. Canavosio, F. Bollati, A. Caceres, and C.-H. Sung. 2005. Tctex-1 has a dynein-independent role in actin remodeling in neurite outgrowth. Developmental Cell 9: 75-85 (COVER).
Dedesma, C., Chuang, J.-Z., Alfinito, P., and C.-H. Sung. 2006. Dynein light chain Tctex-1 identifies neural progenitors in adult brain. J. Comp. Neurol. 496: 773-786.
Yeh, T.-Y. D. Peretti, J.-Z. Chuang, E. Rodriguez-Boulan, and C.-H. Sung. 2006. Regulatory dissociation of Tctex-1 light chain from dynein complex is essential for the apical delivery of rhodopsin. Traffic 7: 1495-1502.
Sachdev, P, Menon, S., Kastner, D. B., Chuang, J.-Z., Yeh, T-Y., Conde, C., Caceres, A., Sung, C-H., and Sakmar, T. P. 2007. G protein ?? subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowth. The EMBO Journal 26, 26212632.
Chuang, J.-Z., Zhao, Y, and Sung, C.-H. 2007. SARA-regulated vesicular targeting underlies formation of the light sensing organelle in mammalian rods. Cell 130:535-547 (COVER).
Alpadi, K., Magupalli, V.G., Kaeppel S., Köblitz, L., Schwarz, K., Seigel, G. M., Sung, C.-H., and Schmitz, F. RIBEYE recruits Munc119, a mammalian ortholog of the C. elegans protein unc119, to synaptic ribbons of photoreceptor synapses (J. Biol. Chem. 2008.Jul 29. [Epub ahead of print])
Martín-Cófreces, N.B., Robles-Valero, J., Cabrero, J. M., Mittelbrunn, M., Gordón-Alonso, M., Sung, C.-H., Alarcón, B., Vázquez, J., and Sánchez Madrid, F. 2008. MTOC translocation modulates IS formation and controls sustained T cell signaling. J. Cell Biol. 182: 951-962.
