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Core Research Facilities

IODINATION PROTOCOL FOR USE OF THE IODINATION CORE FACILITY

LOCATION:
Room C-632A 

STAFF:
Martin C. Graham, Director 
Radiation Safety Office/Central Isotope Laboratory 
Room (s): A-0053, A-0049 
Telephone: (212) 746-6964; (212) 746-4569 
Fax: (212) 746-4800 
E-mail: mcgraham@med.cornell.edu

1) All iodinations are to be performed either in Room C632A or in a hood with a dedicated duct equipped with an activated charcoal filter. (The efficiency of the filter for trapping iodine is >99.9%) 

2) Notify Radiation Safety of your intention to use the hood and the date of use and the approximate length of time that you will require. 

3) Obtain the key to the facility from Radiation Safety located in Rooms A-0053 and A-0049. 

4) If you are the investigator intending to iodinate, obtain a bioassay of your thyroid. This is performed at the time you pick up the key by Radiation Safety personnel using a thin crystal scintillation survey meter. 

5) Check the hood flow on the dedicated meter. It should be a steady flow that is greater than 125 lineal feet per minute. If this is not the case, do not procede any further and notify Radiation Safety at 6-6964 or 6-4569. 

6) Check the hood and surface to be used within the room for contamination. Report and excessive contamination to Radiation Safety. 

7) Perform your iodination, utilizing the lead barriers. Keep the window of the hood as low as practical. Make sure that all surfaces are covered with absorbent material. 

8) After the iodination, place the waste I-125 (or I-131) in the containers provided. Segregate liquids and dry waste. Note the approximate amounts deposited on the inventory card provided. 

9) Check the area for contamination. Clean up any contamination that you are responsible for. Consult with Radiation Safety if the spill is extensive. 

10) Return the key to Radiation Safety. At this time, have your thyroid checked again and the readings recorded. 

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