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NUCLEAR MAGNETIC RESONANCE
CORE FACILITY
PART
I: DESCRIPTION OF SERVICES
Introduction
The
applications for solution NMR have greatly expanded from a traditionally
analytical technique to powerful biological tool for the investigation
of biomolecule structure, dynamics, and stability. A wide variety
of experiments exist for analyzing biological molecules using NMR.
Basic 1D and 2D applications can often be employed on small proteins
and other compounds in a matter of hours to assess: composition,
structure, sample purity, mutational effects and ligand binding
interactions. More involved multidimensional NMR applications can
be employed for protein structure determination and dynamics investigations.
Collaborations.
The variety of NMR applications require differing levels of expertise
for collecting and analyzing the NMR data. Collaborations with NMR
facility members may be advised, depending upon the expertise of
the user. Co-authorship of potential manuscripts should be discussed
at an early stage in projects.
Assisted
and Unassisted NMR use. Users are encouraged to learn NMR data collection
and processing techniques. Training sessions on the basic use of
the NMR spectrometer will be offered at intervals throughout the
year for new users. Only trained users will be allowed to independently
operate the NMR spectrometer.
Location:
E-002,
NMR Laboratory
E-005, Facility Office
Map
Staff:
| Clay Bracken |
Assistant Professor |
746-6473, office |
746-6475 lab |
| David Eliezer |
Assistant Professor |
746-6427 |
| Frederick R. Maxfield |
Professor & Chairman |
746-6405 |
Facility
Description:
Instrumentation
The
facility consists of a Varian Unity Inova 600 MHz NMR spectrometer,
capable of state-of-the-art solution NMR experiments.
Organization
and Services Provided:
PART
III: Procedures for Use of the NMR Facility
Contact:
| Dr. Clay Bracken |
Phone: 746-6473 |
| Assistant Professor |
FAX: 746-8329 |
| Department of Biochemistry |
E-005 |
| Email: clay@bronx.med.cornell.edu |
Scheduling:
The facility is open Monday-Friday 9 am-5 PM, and after hours at
the discretion of the staff. Scheduling is done by Dr. Bracken.
Users will be billed for reserved time unless it is canceled three
days in advance or used by another group.
Billing:
Billing will be generated at the end of each month and processed
through the Biochemistry Department. 
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