Publications

Xie Q, Cho H, Calaycay J, Mumford R, Swiderek K, Lee T, Ding A, Troso T, Nathan C. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 256:225-228, 1992

MacMicking J, Nathan C, Hom G, Chartrain N, Trumbauer M, Stevens K, Xie Q, Sokol K, Fletcher D, Hutchinson N, Chen H, Mudgett J. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81:641-650, 1995

MacMicking J, North R, LaCourse R, Mudgett J, Shah S, Nathan C. Identification of NOS2 as a protective locus against tuberculosis. Proc Natl Acad Sci USA 94:5243-5248, 1997

Bryk R, Griffin P and Nathan C. Peroxynitrite reductase activity of bacterial peroxiredoxins. Nature 407, 211-215, 2000

Nathan, C. Inflammation: Points of control. Nature 420: 846-852, 2002.

Bryk, R, Lima C, Erdjument-Bromage H, Tempst P. Nathan C. Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein. Science 295: 1073-1077, 2002.

Darwin KH, Ehrt S, Gutierrez-Ramos JC, Weich N, Nathan C. The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide. Science 302: 1963-1966, 2003.

Nathan C. Antibiotics at the crossroads. Nature 431: 899-902, 2004.

Nathan, C. Neutrophils and immunity: Challenges and opportunities. Nature Reviews Immunol. 6: 173-182, 2006.

Nathan, C. Aligning pharmaceutical innovation with medical need. Nature Medicine 13: 304-308, 2007.

Bryk R, Gold B, Venugopal A, Singh J, Samy R, Pupek K, Cao H, Popescu C, Gurney M, Hotha S, Cherian J, Rhee K, Ly L, Converse P, Ehrt S, Vandal O, Jiang X, Schneider J, Lin G, Nathan C. Selective killing of non-replicating mycobacteria. Cell Host and Microbe 3: 137-145, 2008

Gold, B., H. Deng, R. Bryk, D. Vargas, D. Eliezer, J. Roberts, X. Jiang, and C. Nathan. Identification of a copper-binding metallothionein in pathogenic mycobacteria. Nature Chemical Biology 4: 609-613, 2008.

Vandal OH, Pierini LM, Schnappinger D, Nathan CF, Ehrt SE. A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis. Nature Med. 14: 849-854, 2008., 2008

Nathan, C. Taming tuberculosis: A challenge for science and society. Cell Host and Microbe 5: 220-4, 2009. 

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