Appointments
 
Attending Physician

O. Wayne Isom Professor of Medicine

Co-chief, Division Of Hematology And Medical Oncology

Professor of Medicine

 
Weill Cornell \r\nPhysician
   

Hempstead, Barbara Louise
 (212) 746-6215  (212) 746-8866

Lee, R, Kermani, P, Teng, K, Hempstead, BL 2001. The pro-NGF precursor dictates pro-apoptotic or pro-survival outcomes through differential receptor binding. Science 294: 1945-1948

Nykjaer, A, Lee R, , Teng KK, Nielsen MS, Jansen P, Madsen P, Jacobsen C, Kliemannel M, Wilnow TE Hempstead BL, Petersen CM. 2004. Sortilin is essential for proNGF induced neuronal cell death. Nature 427: 843-8

Pang, PMW, Teng H, Teng, KK, Cheng, S. Zaitsev E, Sakata K, Yung WH, Hempstead BL, Lu B. 2005. Proteolytic conversion from pro-to-mature BDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science, 306:487-91.

Kermani, P, Rafii D, Jin DK, Whitlock P, Schaffer W, Chiang A, Vincent L, Friedrich M, Shido K, Hackett NR, Crystal RG, Raffi S, Hempstead BL 2005. Neurotrophins promote revascularization by local recruitment of TrkB+endothelial cells and systemic mobilization of hematopoietic progenitors. J.Clin Invest 115:653-63.

Teng HK, Teng KK, Lee R, Wright S, Tevar S, Almeida RD, Kermani P, Torkin R, Chen ZY, Lee FS, Kraemer RT, Nykjaer A, Hempstead BL. 2005 ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci 25:5455-63.

Woo NH, Teng HK, Siao CJ, Chiaruttini C, Pang PT, Milner TA, Hempstead BL, Lu B. 2005. Activation of p75(NTR) by proBDNF facilitates hippocampal long-term depression. Nature Neuroscience. 8:1069-77.

Kraemer R, Baker PJ, Kent KCm Ye Y, Han JJ, Tejada R, Silane M, Upmacis R, Deeb R, Chen Y, Levine DM, Hempstead B. 2005 Decreased neurotrophin TrkB receptor expression reduces lesion size in the apolipoproteinE-null mutant mouse. Circulation 112:3644-53.

Hempstead BL. 2006. Dissecting the diverse actions of pro- and mature neurotrophins. Curr Alzheimer Res 3(1):19-24.

Chen ZY, Jing D, Bath KG, Ieraci A, Khan T, Siao CJ, Herrera DG, Toth M, Yang C, McEwen BS, Hempstead BL, Lee FS. 2006 Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior.Science. 314:140-3.

Kermany, P, Hempstead B. 2007 Brain-derived neurotrophic factor: a newly described mediator of angiogenesis. Trends in Cardiovasc Med. 17:140-3.
   
   
 
 
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