Publications

Ding, A., C. F. Nathan, and D. Stuehr. (1988) Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. J. Immunol. 141:2407.

Tsunawaki, S., M. Sporn, A. Ding, and C. F. Nathan. (1988) Deactivation of macrophages by transforming growth factor-beta. Nature 334:260-262.

Ding, A., and C. F. Nathan. (1988) Analysis of the nonfunctional respiratory burst in murine Kupffer cells. J. Exp. Med. 167:1154-1170.

Ding, A., F. Porteu, E. Sanchez and C. Nathan. (1990) Shared actions of endotoxin and taxol on TNF receptor and TNF release. Science 248:370.

Xie, Q.-W., H. J. Cho, J. Calaycay, R. A. Mumford, K. M. Swiderek, T. D. Lee, A. Ding, T. Troso, and C. Nathan.(1992) Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 256:225.

Jin, F.-Y., C. F. Nathan, D. Razioch, and A. Ding. (1997) Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide. Cell, 88:417.

Byrd, C. A., W. Bornmann, H. Erdjument-Bromage, P. Tempst, N. Pavletich, C. F. Nathan and A. Ding. (1999) Lipopolysaccharide-mimetic effects of taxol mediated by a heat shock protein. Proc. Natl. Acad. Sci. USA, 96:5645.

Nathan, C. and A. Ding. (2001) TREM-1: A new regulator of innate immunity in sepsis syndrome. Nature Med. 7:530-532.

Zhu, J., C. Nathan, W. Jin, D. Sim, G. S. Ashcroft, S. M. Wahl, L. Lacomis, H. Erdjument-Bromage, P. Tempst, C. D. Wright and A. Ding. (2002) Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair. Cell 111:867.40.

Shi, S., C. Nathan, D. Schnappinger, J. Drenkow, M. Fuortes, E. Block, A. Ding, T.R. Gingeras, G. Schoolnik, S. Akira, K. Takeda and S. Ehrt. (2003) MyD88 primes macrophage for full-scale activation by interferon-? yet mediates few responses to Mycobacterium tuberculosis. J. Exp. Med., 198:987-997.

Ding, A., H Yu, J Yang, S Shi and S Ehrt. (2005) Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88. Immunology, 116:381-389.

Sun D. and A. Ding (2006) MyD88 mediates stabilization of cytokine and chemokine mRNAs induced by interferon-g. Nat. Immunol., 7:375-381.

Xu.W, B. He, A. Chiu, M. Buldys, M. Shen, A. Ding, D.M. Knowles, P. Santini, and A. Cerutti. (2007) Epithelial cells trigger frontline immunoglobulin class switching through an SLPI-regulated pathway: a tail from the crypt. Nat. Immunol., 8:294-303.

Kim, Y., P. Zhou, L. Qian, J.-Z. Chuang, J. Lee, C. Li, C. Iadecola, C. Nathan and A. Ding. (2007) MyD88-5 links mitochondria, microtubules and JNK3 in neurons and regulates neuronal survival. J. Exp. Med., 204:2063-2074.

Ghasemlou, N., J. Yang, R. López-Vales, H. Haber, T. Thuraisingam, G. He, D. Radzioch, A. Ding and S. David. (2010) Secretory leukocyte protease inhibitor reduces secondary damage and promotes functional recovery after spinal cord injury, Brain, 133:126-138.

Yin, F., R. Banerjee, B. Thomas, P. Zhou, L. Qian, T. Jia, X. Ma, Y. Ma, C. Iadecola, M. F. Beal, C. Nathan and A. Ding. (2010) Exaggerated inflammation, impaired host defense and neuropathology in progranulin-deficient mice. J. Exp. Med., 207:117-128.

Nathan, C. and A. Ding. (2010) Non-resolution of inflammation. Cell, 140: 871-882.

Nathan, C. and A. Ding. (2010) Snapshot: reactive oxygen intermediates. Cell, 140: 952-952e2.

Yin, F., M. Dumont, R. Banerjee, Y. Ma, H. Li, M.T. Lin, M.F. Beal, C. Nathan, B. Thomas, B. and A. Ding. (2010) Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia. FASEB J., 24:4639-47.

He, G., Y. Ma, S. Chou, H. Li, C. Yang, J. Z. Chuang, C. H. Sung and A. Ding. (2011) A role of CLIC4 in the host innate responses to bacterial lipopolysaccharide. Eur. J. Immunol., 41:1221-1230.

Tang, W., Y. Lu, Q. Tian, Y. Zhang, F. Guo, G. Liu, N. M. Syed, Y. Lai, E. A. Lin, L. Kong, J. Su, F. Yin, A. Ding, A. Zanin-Zhorov, M. L. Dustin, J. Tao, J. Craft, Z. Yin, S. B. Abramson, X. Yu, C. Liu. (2011) The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science 332: 478-484.

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