Community and Public Health Programs
Current Grants
Clinton Global Initiative for a Translational Research Center for Viral Hepatitis
Ann Beeder, M.D., Andrew H. Talal, M.D., Co-PIs
Jill Iscol, Ed.D., IF Hummingbird Foundation
The objectives of this 2-year grant are to implement treatment algorithms for viral hepatitis that could serve as a model for resource poor areas ranging from inner cities in the United States to developing countries with limited health care infrastructure, and to create a world-class biomedical translational research facility devoted to viral hepatitis to facilitate the rapid validation of novel prognostic and treatment biomarkers that can be used to change patient management. Approximately 300 methadone-maintained patients at the NewYork-Presbyterian Hospital will be screened for viral hepatitis. Those who show signs of having been exposed to viral hepatitis will be evaluated to assess disease severity. Treatment will be prescribed as indicated. Treated patients will have blood obtained for measure of potentially promising biomarkers of treatment outcome.
Center of Excellence in Health Disparities Research
Carla Boutin-Foster, M.D., M.S., PI
National Center on Minority Health and Health Disparities (NCMHD)
07/25/09 – 05/31/14
This is an application to establish a Comprehensive Center of Excellence in Disparities Research and Community Engagement (CEDREC) as a consortium between Weill Cornell Medical College, Hunter College School of Nursing-City University of New York, Lincoln Medical and Mental Health Center, and the Center for Healthful Behavior Change at New York University School of Medicine.
Identification and Treatment of Acute HCV in Active IVDUs
Brian Edlin, M.D., PI
Immune Responses to Influenza Vaccination in Opioid Users
Mirella Salvatore, M.D., PI
Weill Cornell CTSC/National Center for Research Resources/NIH
6/1/2010-5/31/2012
This pilot study will examine whether patients actively using heroin have defective humoral and/or cellular immune response to inactivated influenza vaccine compared with long-term methadone patients and non-user controls.
Integrated versus Separate Care for Hepatitis C, Substance Abuse and HIV Prevention (R01)
Brian Edlin, M.D., PI (SUNY Downstate); Ann Beeder, M.D., WCMC Subcontract PI; Bruce Schackman, Ph.D, Co-Investigator; Steve J. Ferrando, M.D., Co-Investigator
National Institute on Drug Abuse/National Institutes of Health
4/1/2010 – 1/31/2015
The study will examine the feasibility, acceptability, safety, effectiveness, and cost of an Integrated Care Program for hepatitis C or HCV/HIV coinfection, addiction, and HIV prevention in active injection drug users (IDUs), in comparison with standard, separate treatment for each of these conditions.
SCALE: Small Changes and Lasting Effects
Mary Charlson, M.D., PI
NIH/NHLBI
The goal is to establish an infrastructure for translating basic and social science discoveries to develop effective behavioral interventions targeted at preventing and treating obesity. The study is part of an interdisciplinary Center for Behavior Intervention Development to reduce obesity among African-American and Latino New Yorkers. This is a joint program with the University in Ithaca, Lincoln Hospital in the Bronx, and Renaissance Health Systems.
Targeted Vector Delivery for Rapid Protection from Infectious Diseases
Mirella Salvatore, MD, PI
Feldstein Medical Foundation
6/1/2012 – 5/30/2013
The study will develop and test a novel passive immunotherapy approach using integrase-defective lentiviral vectors (ID-LV) that produce therapeutic antibodies, using influenza virus as a model. This study, in conjunction with the investigator's previous studies, will advance the field of passive immunotherapy and hold excellent promise to be rapidly “translated” to patient populations.
Treatment of Hepatitis C in Underserved Populations
Brian Edlin, M.D., PI;
Brandon Aden, MD, MPH, Mirella Salvatore, MD, Stephen Ferrando, MD, Ann Beeder, MD, Andrew Talal, MD, MPH, Ira Jacobson, MD, Michael Carden, MPH, and Marla Shu, MPH, Co-Investigators
Patrick Raue, PhD, PI
NIH/NIMH
The proposed study will evaluate the impact of a two-session shared decision making nursing intervention among depressed elderly primary care patients, in comparison to Physician-Recommended Treatment (PRT), on patient adherence to antidepressant medication or psychotherapy and on reduction in depressive symptoms.
Emilio Carrillo, M.D., PI
New York State Department of Mental Health and Hygiene
The goal is to evaluate the impact of a community health worker program on diabetes management among African-American and Latino adults with diabetes.
Brooklyn Public Health Office, PI
New York State Department of Mental Health and Hygiene
The goal of this project is to develop, implement, and evaluate a wellness Brooklyn for African-American men in faith-based settings.
Recent Grants
Building Bridges, Building Knowledge, Building Health Coalition
Emilio Carrillo, M.D., Co-PI
Minority Health Community Partnerships, New York State Department of Health
2/2006-2/2011
Project funded to create a social health movement among diabetes patients and families in northern Manhattan to understand and utilize preventive health interventions associated with diabetes and obesity and reduce ethnic disparities by 2011.
Clinical Translational Research Award
Carla
Boutin-Foster, M.D., PI
The goal of the project was to identity the attitudes and perspectives surrounding decision making in cardiac revascularization procedures.
Clinical Translational Research Award
Carla Boutin-Foster, M.D., Shefali Balavenkatesh Kanna, M.B.,B.S., Co-PIs
The goal of the study was to conduct a community wide survey on barriers to weight loss among overweight and obese residents in the South Bronx.
Cost-effectiveness of Buprenorphine Treatment for Opioid Dependence
Ann Beeder, M.D., Co-Investigator (In collaboration with Bruce Schackman, Ph.D. [PI])
Robert Wood Johnson Foundation
10/01/07-03/31/10
The objective of this project is to develop and use a cost-effectiveness computer simulation model of opioid dependence treatment in the U.S. to evaluate buprenorphine maintenance treatment compared to methadone maintenance treatment and no treatment options, identify how costs and benefits are allocated among government or health insurance payers and patients, and determine the impact of regulatory barriers on cost-effectiveness results.
Integrase-Defective Lentiviral Based Influenza Vaccines
Mirella Salvatore, M.D., PI
National Institute of Allergy and Infectious Diseases/National Institutes of Health
7/16/2009-6/30/2011
The objective of this study is to develop a non-integrating lentiviral vector in the creation of a vaccine for influenza. The researchers will test the vector using the influenza virus on mice.
Redes en Acción: National Latino Cancer Research Network - Breast and Colorectal Cancer
Emilio Carrillo, M.D. (Subcontract with Baylor College of Medicine. P.I.: Amelie Ramirez, Dr.P.H.)
National Cancer Institute
4/1/2005-3/31/2010
Cancer prevention among Latina Women
