Listed below are some recent publications from the Pharmacology Graduate Students.

(in alphabetical order)
 

 

Kamenetsky, M., Middelhaufe, S. Bank, E.M., Levin, L.R., Buck, J., and Steegborn, C. (2006). Molecular details of cAMP generation in mammalian cells: A tale of two systems. J. Mol. Biol. 362: 623-629.

Tatapudy, S., Bruening, S., Gleason, G., and Toth, M. (2008) Validation and use of a computer-assisted counting procedure to quantify BrdU-labeled proliferating cells in the early postnatal mouse hippocampus. J Neurosci Methods. In Press.

Bruening S., Oh E., Hetzenauer A., Escobar-Alvarez S., Westphalen R.I., Hemmings H.C. Jr, Singewald N., Shippenberg T., and Toth M. (2006) The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system. J Neurochem. 99(3):892-899.

Kushnir-Sukhov, N. M., Gilfillan, A. M., Coleman, J. W., Brown, J. M., Bruening, S., Toth, M., and Metcalfe, D. D. (2006) 5-hydroxytryptamine induces mast cell adhesion and migration. J Immunol, 177: 6422-6432.

Guasparri, I., Bubman, D., and Cesarman, E. (2008) EBV LMP2A affects LMP1-mediated NF-kappaB signaling and survival of lymphoma cells by regulating TRAF2 expression. Blood, 111: 3813-3820.

Bubman, D., Guasparri, I., and Cesarman, E. (2007) Deregulation of c-Myc in primary effusion lymphoma by Kaposi's sarcoma herpesvirus latency-associated nuclear antigen. Oncogene, 26: 4979-4986.

Fan W, Bubman D, Chadburn A, Harrington WJ Jr, Cesarman E, Knowles DM. (2005) Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association. J Virol. 79(2):1244-51.

Bubman D, Cesarman E. (2003) Pathogenesis of Kaposi's sarcoma. Hematol Oncol Clin North Am 17:717-45.

Birk AV, Bubman D, Broekman MJ, Robertson HD, Drosopoulos JH, Marcus AJ, Szeto HH. (2002) Role of a novel soluble nucleotide phospho-hydrolase from sheep plasma in inhibition of platelet reactivity: hemostasis, thrombosis, and vascular biology. J Lab Clin Med 139:116-24.

Chaloupka, J.A., Bullock, S.A., Iourgenko, V., Levin, L.R., and Buck, J. (2006). Autoinhibitory regulation of soluble adenylyl cyclase. Mol. Repro & Dev. 73:361-368.

Mogenson, E.G., Janbon, G., Chaloupka, J., Steegborn, C., Fu, M.S., Moyrand, F., Klengel, T., Pearson. D.S., Geeves, M.A., Buck. J., Levin, L.R.and Muhlschlegel, F.A. (2006). Cryptococcus senses CO2  through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1. Eukaryotic Cell 5:103-111.

Klengel, T.*, Liang, W-J.*, Chaloupka, J.A.*, Ruoff, C.,Schroppel, K., Naglik, J.R., Eckert, S.E., Gweiss, E., Haynes, K., Tuitte, M.F., Levin, L.R., Buck, J., and Muhlschlegel, F.A. (2005). Fungal adenylyl cyclase integrates CO2  sensing with CAMP  aignalling and virulence. Curr. Biol. 15:2021-2026. (*contributed to equally).  

Choi, E. and Abbott, G. W. (2007) The MiRP2-Kv3.4 potassium channel: muscling in on Alzheimer's disease. Mol Pharmacol, 72: 499-501.

Antczak, C., Shum, D., Escobar, S., Bassit, B., Kim, E., Seshan, V. E., Wu, N., Yang, G., Ouerfelli, O., Li, Y. M., Scheinberg, D. A., and Djaballah, H. (2007) High-throughput identification of inhibitors of human mitochondrial peptide deformylase. J Biomol Screen, 12: 521-535.

Bruening S., Oh E., Hetzenauer A., Escobar-Alvarez S., Westphalen R.I., Hemmings H.C. Jr, Singewald N., Shippenberg T., and Toth M. (2006) The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system. J Neurochem. 99(3):892-899.

Escorcia, F. E., McDevitt, M. R., Villa, C. H., and Scheinberg, D. A. (2007) Targeted nanomaterials for radiotherapy. Nanomed, 2: 805-815.

Zippin JH, Farrell J, Huron DR, Kamenetsky M, Hess KC, Fischman DA, Levin LR, Buck J. (2004) Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain. J Cell Biol. 164(4):527-34.

Mahurter L., Garceau C., Marino J., Schmidhammer H., Toth G., Pasternak G.W. (2006) Separation of binding affinity and intrinsic activity of the potent mu opioid 14-methoxymetopon. J Pharmacol Exp Ther. 319(1):247-253.

Gillespie, R. F. and Gudas, L. J. (2007) Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements. J Biol Chem, 282: 33421-33434.

Gillespie, R. F. and Gudas, L. J. (2007) Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells. J Mol Biol, 372: 298-316.

Tatapudy, S., Bruening, S., Gleason, G., and Toth, M. (2008) Validation and use of a computer-assisted counting procedure to quantify BrdU-labeled proliferating cells in the early postnatal mouse hippocampus. J Neurosci Methods. In Press.

Gordon, E., Panaghie, G., Deng, L., Bee, K. J., Roepke, T. K., Krogh-Madsen, T., Christini, D. J., Ostrer, H., Basson, C. T., Chung, W., and Abbott, G. W. (2008) A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance. Cardiovasc Res, 77: 98-106.

Abbott, P., Gordon, E., and Davison, J. (2008) Expanding roles of Aboriginal health workers in the primary care setting: seeking recognition. Contemp Nurse, 27: 157-164.

Abbott, P., Gordon, E., and Davison, J. (2007) Expanding roles of Aboriginal health workers in the primary care setting: seeking recognition. Contemp Nurse, 26: 66-73.

Gordon E., Roepke T.K., and Abbott G.W. (2006). Endogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studies. Biophysical Journal 90(4):1223-31.

Gordon E.,Cohen J.L., Engel R., and Abbott G.W. (2006). 1,4-diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers. Molecular Pharmacology 69(3):718-726.

Anantharam A., Lewis A., Panaghie G., Gordon E., McCrossan Z.A., Lerner D.J., and Abbott G.W. (2003) RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies. J Biol Chem 278:11739-45.

Wu, K.Y., Zippin, J.H., Huron DR, Kamenetsky, M., Hengst, U., Buck, J., Levin, L.R., and Jaffrey, S.R. (2006). Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nature Neuroscience. 9:1257-1264.

Zippin JH, Farrell J, Huron DR, Kamenetsky M, Hess KC, Fischman DA, Levin LR, Buck J. (2004) Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain. J Cell Biol. 164(4):527-34.

Huron DR, Gorre ME, Kraker AJ, Sawyers CL, Rosen N, & Moasser, MM. (2003) A Novel Pyridopyrimidine Inhibitor of Abl Kinase Is a Picomolar Inhibitor of Bcr-abl-driven K562 Cells and Is Effective against STI571-resistant Bcr-abl Mutants. Clin Cancer Res 9:1267-73.

McDevitt, M. R., Chattopadhyay, D., Jaggi, J. S., Finn, R. D., Zanzonico, P. B., Villa, C., Rey, D., Mendenhall, J., Batt, C. A., Njardarson, J. T., and Scheinberg, D. A. (2007) PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice. PLoS ONE, 2: e907.

Jaggi, J. S., Carrasquillo, J. A., Seshan, S. V., Zanzonico, P., Henke, E., Nagel, A., Schwartz, J., Beattie, B., Kappel, B. J., Chattopadhyay, D., Xiao, J., Sgouros, G., Larson, S. M., and Scheinberg, D. A. (2007) Improved tumor imaging and therapy via i.v. IgG-mediated time-sequential modulation of neonatal Fc receptor. J Clin Invest, 117: 2422-2430.

McDevitt, M. R., Chattopadhyay, D., Kappel, B. J., Jaggi, J. S., Schiffman, S. R., Antczak, C., Njardarson, J. T., Brentjens, R., and Scheinberg, D. A. (2007) Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes. J Nucl Med, 48: 1180-1189.

Nolan, D. J., Ciarrocchi, A., Mellick, A. S., Jaggi, J. S., Bambino, K., Gupta, S., Heikamp, E., McDevitt, M. R., Scheinberg, D. A., Benezra, R., and Mittal, V. (2007) Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Genes Dev, 21: 1546-1558.

Singh Jaggi, J., Henke, E., Seshan, S. V., Kappel, B. J., Chattopadhyay, D., May, C., McDevitt, M. R., Nolan, D., Mittal, V., Benezra, R., and Scheinberg, D. A. (2007) Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization. PLoS ONE, 2: e267.

Sofou, S., Kappel, B. J., Jaggi, J. S., McDevitt, M. R., Scheinberg, D. A., and Sgouros, G. (2007) Enhanced retention of the alpha-particle-emitting daughters of Actinium-225 by liposome carriers. Bioconjug Chem, 18: 2061-2067.

Jaggi, J. S., Seshan, S. V., McDevitt, M. R., Sgouros, G., Hyjek, E., and Scheinberg, D. A. (2006) Mitigation of radiation nephropathy after internal alpha-particle irradiation of kidneys. Int J Radiat Oncol Biol Phys, 64: 1503-1512.

Gomez-Nunez, M., Pinilla-Ibarz, J., Dao, T., May, R. J., Pao, M., Jaggi, J. S., and Scheinberg, D. A. (2006) Peptide binding motif predictive algorithms correspond with experimental binding of leukemia vaccine candidate peptides to HLA-A*0201 molecules. Leuk Res, 30: 1293-1298.

Dao, T., Gomez-Nunez, M., Antczak, C., Kappel, B., Jaggi, J. S., Korontsvit, T., Zakhaleva, V., and Scheinberg, D. A. (2005) Natural killer cells license dendritic cell cross-presentation of B lymphoma cell--associated antigens. Clin Cancer Res, 11: 8763-8772.

Jaggi JS, Seshan SV, McDevitt MR, Laperle K, Sgouros G, Scheinberg DA. (2005) Renal Tubulointerstitial Changes after Internal Irradiation with {alpha}-Particle-Emitting Actinium Daughters. J Am Soc Nephrol. 16(9):2677-2689.

Jaggi JS, Kappel BJ, McDevitt MR, Sgouros G, Flombaum CD, Cabassa C and Scheinberg DA. (2005) Efforts to Control the Errant Products of a Targeted In vivo Generator. Cancer Research 65(11):4888-95.

Kamenetsky M, Middelhaufe, S. Bank, E.M., Levin, L.R., Buck, J., and Steegborn, C. (2006). Molecular details of cAMP generation in mammalian cells: A tale of two systems. J Mol Biol. 362: 623-629.

Wu, K.Y, Zippin, J.H., Huron, D.R., Kamenetsky M, Hengst, U., Buck, J., Levin, L.R., and Jaffrey, S.R. (2006). Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nat Neurosci. 9: 1257-1264.

Stessin, A.M., Zippin, J.H., Kamenetsky M, Hess, K.C., Buck, J., and Levin, L.R. (2006). Soluble adenylyl cyclase mediates NGF-induced activation of RAP1. J. Biol. Chem. 281: 17253-17258.

Han H, Stessin A, Roberts J, Hess K, Gautam N, Kamenetsky M, Lou O, Hyde E, Nathan N, Muller WA, Buck J, Levin LR, Nathan C. (2005) Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils. J Exp Med. 202(3):353-61.

Hess KC, Jones BH, Marquez B, Chen Y, Ord TS, Kamenetsky M, Miyamoto C, Zippin JH, Kopf GS, Suarez SS, Levin LR, Williams CJ, Buck J, Moss SB. (2005) The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization. Dev Cell. 9(2):249-59.

Zippin JH, Farrell J, Huron DR, Kamenetsky M, Hess KC, Fischman DA, Levin LR, Buck J. (2004) Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain. J Cell Biol. 164(4):527-34.

Litvin TN, Kamenetsky M, Zarifyan A, Buck J, Levin LR. (2003) Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate. J Biol Chem 278:15922-6.

Zippin JH, Chen Y, Nahirney P, Kamenetsky M, Wuttke MS, Fischman DA, Levin LR, Buck J. (2003) Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains. FASEB J 17:82-4.

Jaggi, J. S., Carrasquillo, J. A., Seshan, S. V., Zanzonico, P., Henke, E., Nagel, A., Schwartz, J., Beattie, B., Kappel, B. J., Chattopadhyay, D., Xiao, J., Sgouros, G., Larson, S. M., and Scheinberg, D. A. (2007) Improved tumor imaging and therapy via i.v. IgG-mediated time-sequential modulation of neonatal Fc receptor. J Clin Invest, 117: 2422-2430.

McDevitt, M. R., Chattopadhyay, D., Kappel, B. J., Jaggi, J. S., Schiffman, S. R., Antczak, C., Njardarson, J. T., Brentjens, R., and Scheinberg, D. A. (2007) Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes. J Nucl Med, 48: 1180-1189.

Singh Jaggi, J., Henke, E., Seshan, S. V., Kappel, B. J., Chattopadhyay, D., May, C., McDevitt, M. R., Nolan, D., Mittal, V., Benezra, R., and Scheinberg, D. A. (2007) Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization. PLoS ONE, 2: e267.

Sofou, S., Kappel, B. J., Jaggi, J. S., McDevitt, M. R., Scheinberg, D. A., and Sgouros, G. (2007) Enhanced retention of the alpha-particle-emitting daughters of Actinium-225 by liposome carriers. Bioconjug Chem, 18: 2061-2067.

Pinilla-Ibarz, J., May, R. J., Korontsvit, T., Gomez, M., Kappel, B., Zakhaleva, V., Zhang, R. H., and Scheinberg, D. A. (2006) Improved human T-cell responses against synthetic HLA-0201 analog peptides derived from the WT1 oncoprotein. Leukemia, 20: 2025-2033.

Kappel, B. J., Pinilla-Ibarz, J., Kochman, A. A., Eng, J. M., Hubbard, V. M., Leiner, I., Pamer, E. G., Heller, G., van den Brink, M. R., and Scheinberg, D. A. (2006) Remodeling specific immunity by use of MHC tetramers: demonstration in a graft-versus-host disease model. Blood, 107: 2045-2051.

Jaggi JS, Kappel BJ, McDevitt MR, Sgouros G, Flombaum CD, Cabassa C and Scheinberg DA. (2005) Efforts to Control the Errant Products of a Targeted In vivo Generator. Cancer Res. 65(11):4888-95.

Dao, T., Gomez-Nunez, M., Antczak, C., Kappel, B., Jaggi, J. S., Korontsvit, T., Zakhaleva, V., and Scheinberg, D. A. (2005) Natural killer cells license dendritic cell cross-presentation of B lymphoma cell--associated antigens. Clin Cancer Res, 11: 8763-8772.

Angeles, A. R., Dorn, D. C., Kou, C. A., Moore, M. A., and Danishefsky, S. J. (2007) Total synthesis of peribysin E necessitates revision of the assignment of its absolute configuration. Angew Chem Int Ed Engl, 46: 1451-1454.

Langton, S. and Gudas, L. J. (2008) CYP26A1 knockout embryonic stem cells exhibit reduced differentiation and growth arrest in response to retinoic acid. Dev Biol, 315: 331-354.

Antczak, C., Jaggi, J. S., LeFave, C. V., Curcio, M. J., McDevitt, M. R., and Scheinberg, D. A. (2006) Influence of the linker on the biodistribution and catabolism of actinium-225 self-immolative tumor-targeted isotope generators. Bioconjug Chem, 17: 1551-1560.

Lahiri, S., Lee, H., Mesicek, J., Fuks, Z., Haimovitz-Friedman, A., Kolesnick, R. N., and Futerman, A. H. (2007) Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine. FEBS Lett, 581: 5289-5294.

Nuriel, T., Deeb, R.S., Hajjar, D.P., and Gross, S.S. (2008) Protein 3-nitrotyrosine in complex biological samples: quantification by high-pressure liquid chromatography/electrochemical detection and emergence of proteomic approaches for unbiased identification of modification sites. Methods Enzymol. 441:1-17.

Paige, J. S. and Jaffrey, S. R. (2007) Pharmacologic manipulation of nitric oxide signaling: targeting NOS dimerization and protein-protein interactions. Curr Top Med Chem, 7: 97-114.

Gordon, E., Panaghie, G., Deng, L., Bee, K. J., Roepke, T. K., Krogh-Madsen, T., Christini, D. J., Ostrer, H., Basson, C. T., Chung, W., and Abbott, G. W. (2008) A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance. Cardiovasc Res, 77: 98-106.

Panaghie, G. and Abbott, G. W. (2007) The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes. J Gen Physiol, 129: 121-133.

Panaghie G.; Tai K.K.; Abbott G.W. (2006) Interaction of KCNE subunits with the KCNQ1 K+ channel pore. Journal of Physiology 570 (Pt 3):455-67.

Panaghie G.; Abbott G.W. (2006) The impact of ancillary subunits on small-molecule interactions with voltage-gated potassium channels. Current Pharmaceutical Design 12(18): 2285-2302.

McCrossan Z.A.; Lewis A.; Panaghie G.; Jordan P.N.; Christini D.J.; Lerner D.J.; Abbott GW. (2003) MinK-related peptide 2 modulates Kv2.1 and Kv3.1 potassium channels in mammalian brain. J Neurosci. 23(22):8077-91.

Anantharam A.; Lewis A.; Panaghie G.; Gordon E.; McCrossan Z.A.; Lerner D.J.; Abbott GW. (2003) RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies. J Biol Chem 278:11739-45.

Vetrivel, K. S., Gong, P., Bowen, J. W., Cheng, H., Chen, Y., Carter, M., Nguyen, P. D., Placanica, L., Wieland, F. T., Li, Y. M., Kounnas, M. Z., and Thinakaran, G. (2007) Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism. Mol Neurodegener, 2: 4.

Platholi, J., Heerdt, P. M., Lim Tung, H. Y., and Hemmings, H. C., Jr. (2008) Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3gamma. J Neurochem. 105(5): 2029-38.

Zhang, T. T., Platholi, J., Heerdt, P. M., Hemmings, H. C., Jr., and Tung, H. Y. (2008) Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation. Metab Brain Dis, 23: 95-104.

Bullock, S. A., Platholi, J., Gjyrezi, A., Heerdt, P. M., Tung, H. Y., and Hemmings, H. C., Jr. (2007) Differential regulation of protein phosphatase-1(I) by neurabin. Biochem Biophys Res Commun, 358: 140-144.

Yun, S.W., Platholi, J., Flaherty, M.S., Fu, W., Kottmann, A.H., and Toth, M. (2006) Fmrp is required for the establishment of the startle response during the critical period of auditory development. Brain Res. 1110(1): 159-65.

Moilanen, S. B.; Potuzak, J. S.; Tan, D. S. (2006) Stereocontrolled synthesis of spiroketals via a Ti(Oi-Pr)4-mediated kinetic spirocyclization of glycal epoxides with retention of configuration. J. Am. Chem. Soc. 128: 1792-1793.

Potuzak, J. S.; Moilanen, S. B.; Tan, D. S. (2005) Stereocontrolled synthesis of spiroketals via a remarkable methanol-induced kinetic spirocyclization reaction.  J. Am. Chem. Soc. 127: 13796-13797.

Potuzak, J. S., Tan, D. S. (2004) Synthesis of C1-alkyl- and acylglycals from glycals using a B-alkyl Suzuki?Miyaura cross coupling approach. Tetrahedron Lett. 45:1797?1801.

Potuzak, J. S., Moilanen, S. B.; Tan, D. S. (2004) Discovery and applications of small molecule probes for studying biological processes. Biotechnol. Genet. Eng. Rev. 21:11-78.

Rotolo, J. A., Maj, J. G., Feldman, R., Ren, D., Haimovitz-Friedman, A., Cordon-Cardo, C., Cheng, E. H., Kolesnick, R., and Fuks, Z. (2008) Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa. Int J Radiat Oncol Biol Phys, 70: 804-815.

Rotolo JA, Zhang J, Donepudi M, Lee H, Fuks Z, Kolesnick R. (2005) Caspase-dependent and-independent activation of acid sphingomyelinase signaling. J Biol Chem. 280(28):26425-26434.

Shang, S., Iwadare, H., Macks, D. E., Ambrosini, L. M., and Tan, D. S. (2007) A unified synthetic approach to polyketides having both skeletal and stereochemical diversity. Org Lett, 9: 1895-1898.

Shang, S. and Tan, D. S. (2005) Advancing chemistry and biology through diversity-oriented synthesis of natural product-like libraries. Curr Opin Chem Biol, 9: 248-258.

Young, J.J.*, Mehdi, A.*, Stohl, L., Levin, L.R., Buck, J., Wagner, J.A., and Stessin A.M. (2007). 'Soluble' adenylyl cyclase-generated cyclic AMP promotes fast migration in PC12 cells. J. Neurosci. Res. 86: 118-124.

Stessin A.M., Zippin, J.H., Kamenetsky M, Hess, K.C., Buck, J., and Levin, L.R. (2006). Soluble adenylyl cyclase mediates NGF-induced activation of RAP1. J. Biol. Chem. 281: 17253-17258.

Han H, Stessin A, Roberts J, Hess K, Gautam N, Kamenetsky M, Lou O, Hyde E, Nathan N, Muller WA, Buck J, Levin LR, Nathan C. (2005) Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils. J Exp Med. 202(3):353-61.

Su, D. and Gudas, L. J. (2008) Retinoic acid receptor gamma activates receptor tyrosine kinase Tie1 gene transcription through transcription factor GATA4 in F9 stem cells. Exp Hematol, 36: 624-641.

Su, D. and Gudas, L. J. (2008) Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells. Biochem Pharmacol, 75: 1129-1160.

Sheren-Manoff, M., Shin, S. J., Su, D., Bok, D., Rando, R. R., and Gudas, L. J. (2006) Reduced lecithin:retinol acyltransferase expression in human breast cancer. Int J Oncol, 29: 1193-1199.

Touma, S. E., Goldberg, J. S., Moench, P., Guo, X., Tickoo, S. K., Gudas, L. J., and Nanus, D. M. (2005) Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model. Clin Cancer Res, 11: 3558-3566.

Escorcia, F. E., McDevitt, M. R., Villa, C. H., and Scheinberg, D. A. (2007) Targeted nanomaterials for radiotherapy. Nanomed, 2: 805-815.

McDevitt, M. R., Chattopadhyay, D., Jaggi, J. S., Finn, R. D., Zanzonico, P. B., Villa, C., Rey, D., Mendenhall, J., Batt, C. A., Njardarson, J. T., and Scheinberg, D. A. (2007) PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice. PLoS ONE, 2: e907.

Kortmansky, J., Shah, M. A., Kaubisch, A., Weyerbacher, A., Yi, S., Tong, W., Sowers, R., Gonen, M., O'Reilly, E., Kemeny, N., Ilson, D. I., Saltz, L. B., Maki, R. G., Kelsen, D. P., and Schwartz, G. K. (2005) Phase I trial of the cyclin-dependent kinase inhibitor and protein kinase C inhibitor 7-hydroxystaurosporine in combination with Fluorouracil in patients with advanced solid tumors. J Clin Oncol, 23: 1875-1884.

Shah, M. A., Kortmansky, J., Motwani, M., Drobnjak, M., Gonen, M., Yi, S., Weyerbacher, A., Cordon-Cardo, C., Lefkowitz, R., Brenner, B., O'Reilly, E., Saltz, L., Tong, W., Kelsen, D. P., and Schwartz, G. K. (2005) A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol. Clin Cancer Res, 11: 3836-3845.

Derakhshan, B., Wille, P. C., and Gross, S. S. (2007) Unbiased identification of cysteine S-nitrosylation sites on proteins. Nat Protoc, 2: 1685-1691.

Wu KY, Zippin, J.H., Huron, D.R., Kamenetsky, M., Hengst, U., Buck, J., Levin, L.R., and Jaffrey, S.R. (2006). Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nature Neuroscience. 9: 1257-1264.

Wu KY, Hengst U, Cox LJ, Macosko EZ, Jeromin A, Urquhart ER, Jaffrey SR. (2005) Local translation of RhoA regulates growth cone collapse. Nature. 436(7053):1020-4.

Garraway, S. M., Xu, Q., and Inturrisi, C. E. (2007) Design and evaluation of small interfering RNAs that target expression of the N-methyl-D-aspartate receptor NR1 subunit gene in the spinal cord dorsal horn. J Pharmacol Exp Ther, 322: 982-988.

Zupan, B. and Toth, M. (2008) Wild-Type Male Offspring of fmr-1(+/-) Mothers Exhibit Characteristics of the Fragile X Phenotype. Neuropsychopharmacology. Jan 2. [ePub ahead of print].