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·         Labitzke, EM, Diani-Moore, S., and Rifkind, A.B. Mitochondial P450-dependent arachidonic acid metabolism by TCDD-induced hepatic CYP1A5; conversion of EETs to DHETs by mitochondrial soluble epoxide hydrolase. Arch. Biochem. Biophys. 2007- published on-line doi:10.1016/j.abb.2007.08.012.

·         Diani-Moore, S.  Papachristou, F., Labitzke, E. and Rifkind, A.B. Induction of CYP1A and CYP2 mediated arachidonic acid epoxygenation and suppression of 20-HETE by imidazole derivatives including the aromatase inhibitor vorozole. Drug Metab. Disp. 34: 1376-1385, 2006. 

·         Rifkind, A.B. CYP1A in TCDD toxicity and in physiology with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates. Drug Metab. Rev., 38, 291-335, 2006.

·         Diani-Moore, S., Labitzke, E,  Brown, R., Garvin, A., Wong, L and Rifkind, A.B. Sunlight generates multiple tryptophan photoproducts eliciting high efficacy CYP1A induction in chick hepatocytes and in vivo, Toxicol.. Sci.  90: 96-110, 2006

·         Wood, E., Broekman, M.J., Kirley, T., Diani-Moore, S., Tickner, M., Drosopoulis, J., Islam, N., Park, J., Marcus, A., and Rifkind, A.B. Cell-type specificity of ectonucleotidase expression and upregulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin.  Arch. Biochem. Biophys. 407: 49-62, 2002.

·         Fan, L., Ovadia, M., Freidman, D.M. and Rifkind, A.B. Ventricular preexcitation sensitive to flecainide in late stage chick embryo ECGs: 2,3,7,8-Tetrachlorodibenzo-p-dioxin impairs inotropic but not chronotropic or dromotropic responses to isoproterenol and confers resistance to flecainide. Toxicol. Appl. Pharmacol. 166: 43-50, 2000.

·         Mahajan, S.S. and Rifkind, A.B. Transcriptional activation of avian CYP1A4 and CYP1A5 by 2,3,7,8 -Tetrachlorodibenzo-p-dioxin: Differences in gene expression and regulation compared to mammalian CYP1A1 and CYP1A2. Toxicol. Appl. Pharmacol. 155: 96-206, 1999.

·         Gannon, M., Gilday, D. and Rifkind, A.B. TCDD induces CYP1A4 and CYP1A5 in chick liver and kidney and only CYP1A4 , an enzyme lacking arachidonic acid epoxygenase activity, in myocardium and vascular endothelium. Toxicol. Appl. Pharmacol. 164: 24-37, 1999.

·         Lee, C.A., Lawrence, B.P., Kerkvliet, N.I. and Rifkind, A.B. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induction of cytochrome P450 dependent arachidonic acid metabolism in mouse liver microsomes; evidence for species specific differences in responses. Toxicol. Appl. Pharmacol. 153: 1-11, 1998.

·         Gilday, D., Gannon, M., Yutzey, K., Bader, D., and Rifkind, A.B. Molecular cloning and expression of two novel avian cytochrome P450 1A enzymes induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin. J. Biol. Chem. 271: 33054-33059, 1996.

·         Canga, L., Paroli, L., Blanck, T.J.J., Silver, R.B. and Rifkind, A.B. 2,3,7,8-Tetrachlorodibenzo-p-dioxin increases cardiac myocyte intracellular calcium and progressively impairs ventricular contractile responses to isoproterenol and to calcium in chick embryo hearts.  Molec Pharmacol  44:1142-1151, 1993.


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