PUBLICATIONS
2008:
Deeb RS, Upmacis RK, Lamon BD, Gross SS, Hajjar DP. "Maintaining equilibrium by selective targeting of cyclooxygenase pathways: promising offensives against vascular injury." Hypertension. 2008 Jan;51(1):1-7. Epub 2007 Nov 12.
Nuriel T, Deeb RS, Hajjar DP, Gross SS. "Protein 3-nitrotyrosine in complex biological samples: quantification by high-pressure liquid chromatography/electrochemical detection and emergence of proteomic approaches for unbiased identification of modification sites." Methods Enzymol. 2008;441:1-17.
Crabtree MJ, Smith CL, Lam G, Goligorsky MS, Gross SS. “Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in no vs. superoxide production by eNOS.” Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1530-40. Epub 2008 Jan 11.
2007:
Upmacis RK, Crabtree MJ, Deeb RS, Shen H, Lane PB, Benguigui LE, Maeda N, Hajjar DP, Gross SS. “Profound biopterin oxidation and protein tyrosine nitration in tissues of ApoE-null mice on an atherogenic diet: contribution of inducible nitric oxide synthase.” Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2878-87. Epub 2007 Aug 31.
Derakhshan B, Wille PC, Gross SS. “Unbiased identification of cysteine S-nitrosylation sites on proteins.” Nat Protoc. 2007;2(7):1685-91.
Derakhshan B, Hao G, Gross SS. “Balancing reactivity against selectivity: the evolution of protein S-nitrosylation as an effector of cell signaling by nitric oxide.” Cardiovasc Res. 2007 Jul 15;75(2):210-9. Epub 2007 May 3.
Dzavík V, Cotter G, Reynolds HR, Alexander JH, Ramanathan K, Stebbins AL, Hathaway D, Farkouh ME, Ohman EM, Baran DA, Prondzinsky R, Panza JA, Cantor WJ, Vered Z, Buller CE, Kleiman NS, Webb JG, Holmes DR, Parrillo JE, Hazen SL, Gross SS, Harrington RA, Hochman JS; Should we inhibit nitric oxide synthase in cardiogenic shock 2 (SHOCK-2) investigators. “Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study.” Eur Heart J. 2007 May;28(9):1109-16. Epub 2007 Apr 25.
---
Gross SS, Hattori Y. (2005) Room for both tyrosine nitration
and cysteine nitrosylation to regulate NFkappaB activity, but perhaps
only one modification at a time.
Cardiovasc Res. 67(4):747-8.
Hattori Y, Akimoto K, Gross SS, Hattori S, Kasai K. (2005)
Angiotensin-II-induced oxidative stress elicits hypoadiponectinaemia in
rats.
Diabetologia. 48(6):1066-74.
Chander PN, Gealekman O, Brodsky SV, Elitok S, Tojo A, Crabtree M,
Gross SS, Goligorsky MS. (2004) Nephropathy in Zucker diabetic fat
rat is associated with oxidative and nitrosative stress: prevention by
chronic therapy with a peroxynitrite scavenger ebselen.
J Am Soc Nephrol. 15(9):2391-403.
Kolinsky MA, Gross SS. (2004) The mechanism of potent GTP
cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine:
requirement of the GTP cyclohydrolase I feedback regulatory protein.
J Biol Chem. 279(39):40677-82.
Hattori Y, Kasai K, Gross SS. (2004) NO suppresses while
peroxynitrite sustains NF-kappaB: a paradigm to rationalize
cytoprotective and cytotoxic actions attributed to NO.
Cardiovasc Res. 63(1):31-40.
Hao, G., Xie, L. and Gross, S.S. (2004) S-nitrosylation of
argininosuccinate synthetase: a mechanism that evolved to limit NO
overproduction.
J. Biol. Chem. 279(35):36192-200.
Gao S., Chen J., Brodsky S.V., Huang H., Adler S., Lee J.H., Dhadwal N.,
Cohen-Gould L., Gross S.S., Goligorsky M.S. (2004) Docking of
eNOS to the mitochondrial outer membrane: A pentabasic amino acid
sequence in the autoinhibitory domain of eNOS targets a proteinase
K-cleavable peptide on the cytoplasmic face of mitochondria.
J. Biol. Chem. 279: 1-7.
Brodsky, S., Gaelikman, O., Chen, J., Kohen, A., Zhang, F., Crabtree,
M., Gross, S.S., Nasjletti, A. and Goligorsky, M.S. (2004)
Premature endothelial cell senescence and vasculaopathy in
obesity-induced diabetes are preventable by chronic treatment with the
peroxynitrite scavenger ebselen.
Circ. Res. 94: 1-8.
Felsen D, Schulsinger D, Gross SS, Kim FY, Marion D, Vaughan ED Jr. (2003) Renal hemodynamic and ureteral pressure changes in response to ureteral obstruction: the role of nitric oxide. J Urol. 169:373-6.
Felsen D, Dardashti K, Ostad M, Lemer ML, Gross SS, Chen J, Vaughan ED Jr, Poppas DP. (2003) Inducible nitric oxide synthase promotes pathophysiological consequences of experimental bladder outlet obstruction. J Urol. 169:1569-72.
Crabtree M, Hao G, Gross SS. (2003) Detection of cysteine S-nitrosylation and tyrosine
3-nitration in kidney proteins.
Methods Mol Med. 86:373-84.
Chen J, Brodsky SV, Goligorsky DM, Hampel DJ, Li H, Gross SS, Goligorsky
MS. (2002) Glycated collagen I induces premature senescence-like phenotypic
changes in endothelial cells.
Circ Res. 90(12):1290-8.
Lane, P and Gross, SS (2002) Disabling a C-terminal autoinhibitory control element in endotelial NO synthase by phosphorylation provides a molecular explanation for activation of vascular NOsynthesis by diverse physiological stimuli. J. Biol. Chem. 277:19087-94.
Weissman, BA, Jones, C.L., Liu, Q., Gross SS. (2002) Activation and inactivation of neuronal nitric oxide synthase: characterization of Ca(2+)-dependent [125I]Calmodulin binding. Eur J Pharmacol. 435: 9-18.
