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Solid Tumors

Lung Cancer

1

Disease Status and/or Stage Non-Small Cell Lung Cancer
Protocol Title CALGB 140503: A Phase III Randomized Trial of Lobectomy versus Sublobar Resection for Small (<2cm) Peripheral Non-Small Cell Lung Cancer
PI Nasser Altorki, MD
Contact Estella Hernandez, RN
212-746-3328
Key Eligibility Peripheral lung nodule less than or equal to 2 cm on preoperative CT scan and presumed to be lung cancer. No prior malignancy within 5 years other than non-melanoma skin cancer, superficial bladder cancer, or CIS of the cervix. The tumor location must be suitable for either lobar or sublobar resection (wedge or segment)
Treatment Overview Patients will be randomized to receive a Lobectomy or a Sublobar Resection

2

Disease Status and/or Stage Progressive disease after therapies with curative potential or approval salvage regimen
Protocol Title A Phase I/II, Open-Label, Dose Escalation Study of CDX-1401 in PAtients with Malignancies Known to Express NY-ESO-1
PI Ellen Chuang, MD
Contact Marta Cobham, RN
212-821-0780

3

Disease Status and/or Stage Unresectable, Locally Advanced, Stage III Non-Small Cell Lung Cancer
Protocol Title Phase 3 Study of Pemetrexed, Cisplatin, and Radiotherapy Followed by Consolidation Pemetrexed versus Etoposide, Cisplatin, and Radiotherapy Followed by Consolidation Cytotoxic Chemotherapy of Choice in Patients with Unresectable, Locally Advanced, Stage III Non-Small Cell Lung Cancer Other than Predominantly Squamous Cell Histology
PI Ronald Scheff, MD
Contact Kristen Petrillo, RN
212-746-5430

4

Disease Status and/or Stage Stage IIIB/IV or Recurrent, Unresectable Non-Small Cell Lung Cancer
Protocol Title A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 2 Study of the Efficacy and Safety of Apricoxib in Combination with either Docetaxel or Pemetrexed in Non-Small Cell Lung Cancer Patients
PI Bryan Schneider, MD
Contact Kristen Petrillo, RN
212-746-5430

5

Disease Status and/or Stage Metastatic Solid Tumors
Protocol Title A Phase I Study of 177Lu Radiolabeled Monoclonal Antibody HuJ591-GS (177Lu-J591) in Patients with Nonprostate Metastatic Solid Tumors: A Pilot Study
PI Scott Tagawa, MD
Contact Kristen Petrillo, RN
212-746-5430

6

Disease Status and/or Stage Chemotherapy-Induced Peripheral Neuropathy
Protocol Title CALGB 170601: A Phase III Double Blind Trial of Oral Duloxetine for Treatment of Pain Associated with Chemotherapy-Induced Peripheral Neuropathy (CIPN)
PI Elizabeth Popa, MD
Contact Kristen Petrillo, RN
212-746-5430

7

Disease Status and/or Stage Chemotherapy-Induced Peripheral Neuropathy
Protocol Title CALGB 170601: A Phase III Double Blind Trial of Oral Duloxetine for Treatment of Pain Associated with Chemotherapy-Induced Peripheral Neuropathy (CIPN)
PI Bryan Schneider, M.D.
Contact Kristen Petrillo, RN
212-746-5430
  Last updated: May 26, 2010
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