McGraw Lab
Department of Biochemistry
Weill Medical College of Cornell University
Endocytic Membrane
Traffic
My lab studies
endocytic membrane trafficking. Eukaryotic
cells internalize extracellular ligands such as proteins and nutrients by
a process called endocytosis. Endocytosis also mediates the internalization of cellular membrane
proteins, such as transporters and receptors, into tubular-vesicular structures
called endosomes. In addition
to playing a key role in many constitutive cellular functions (i.e., nutrient
uptake), the endocytic system is involved in a number of important regulated
processes. Membrane trafficking
is the subject of intense study. There are two main projects ongoing in
my lab. For a discussion of these
projects please click on the links below.
Links
to affiliated graduate programs
Presentations
(Teaching)